5-METHYL-2,1,3-BENZOTHIADIAZOLE
- Product Name
- 5-METHYL-2,1,3-BENZOTHIADIAZOLE
- CAS No.
- 1457-93-8
- Chemical Name
- 5-METHYL-2,1,3-BENZOTHIADIAZOLE
- Synonyms
- BUTTPARK 33\04-40;5-Methylpiazthiole;5-METHYL-2,1,3-BENZOTHIADIAZOLE;5-METHYLBENZO-2,1,3-THIADIAZOLE;5-methyl-benzo[1,2,5]thiadiazole;2,1,3-Benzothiadiazole, 5-methyl-;5-Methylbenzo[c][1,2,5]thiadiazole
- CBNumber
- CB0330127
- Molecular Formula
- C7H6N2S
- Formula Weight
- 150.2
- MOL File
- 1457-93-8.mol
5-METHYL-2,1,3-BENZOTHIADIAZOLE Property
- Melting point:
- 31-32°
- Boiling point:
- 62 °C
- Density
- 1.297±0.06 g/cm3 (20 ºC 760 Torr)
- Flash point:
- 92.6±9.1℃
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 0.59±0.47(Predicted)
- Appearance
- Light yellow to yellow Solid-Liquid Mixture
- CAS DataBase Reference
- 1457-93-8
Safety
- Hazard Note
- Harmful
- HazardClass
- IRRITANT
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- OR26809
- Product name
- 5-Methyl-2,1,3-benzothiadiazole
- Packaging
- 250mg
- Price
- $24
- Updated
- 2021/12/16
- Product number
- 4428AD
- Product name
- 5-Methyl-2,1,3-benzothiadiazole
- Packaging
- 250mg
- Price
- $25
- Updated
- 2021/12/16
- Product number
- 7H70-1-W5
- Product name
- 5-Methyl-2,1,3-benzothiadiazole
- Packaging
- 250mg
- Price
- $26
- Updated
- 2021/12/16
- Product number
- 047293
- Product name
- 5-Methyl-2,1,3-benzothiadiazole
- Purity
- >95%
- Packaging
- 500mg
- Price
- $47
- Updated
- 2021/12/16
- Product number
- 047293
- Product name
- 5-Methyl-2,1,3-benzothiadiazole
- Purity
- >95%
- Packaging
- 1g
- Price
- $72
- Updated
- 2021/12/16
5-METHYL-2,1,3-BENZOTHIADIAZOLE Chemical Properties,Usage,Production
Definition
ChEBI: 5-Methyl-2,1,3-benzothiadiazole is a benzothiadiazole.
Synthesis
496-72-0
1457-93-8
(1) To a 250 mL three-neck flask was added 4-methylbenzene-1,2-diamine (3.75 g, 30 mmol) and dichloromethane (60 mL) followed by trimethylamine (13.14 g, 130 mmol). The mixture was stirred until 4-methylbenzene-1,2-diamine was completely dissolved. Under stirring, sulfurous dichloride (11.47 g, 100 mmol) was slowly added dropwise and then the reaction mixture was heated to reflux for 5 hours. Upon completion of the reaction, the reaction was quenched with 1 mol/L sodium hydroxide solution and subsequently extracted with dichloromethane (30 mL x 3). The organic phases were combined and concentrated by rotary evaporator. The crude product was purified by silica gel column chromatography using petroleum ether as eluent to afford brown needle-like crystals of 5-methyl-2,1,3-benzothiadiazole (3.69 g, 82% yield). The product characterization data were as follows: melting point 33-34 °C; 1H NMR (CDCl3, 400 MHz, TMS): δ 7.88 (d, 1H, J = 9 Hz), 7.76 (s, 1H), 7.43 (d, 1H, J = 9 Hz), 2.55 (s, 3H); 13C NMR (CDCl3, 100 MHz, TMS): δ 155.31, 153.54, 139.94, 132.41, 120.66, 119.76, 21.91; EIMS [M+]: calculated value 150.0252, measured value 150.0251.
References
[1] Tetrahedron, 2016, vol. 72, # 9, p. 1244 - 1248
[2] Tetrahedron, 2017, vol. 73, # 19, p. 2824 - 2830
[3] Journal of Polymer Science, Part A: Polymer Chemistry, 2016, vol. 54, # 5, p. 668 - 677
[4] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 4, p. 657 - 667
[5] Chemische Berichte, 1889, vol. 22, p. 2897
5-METHYL-2,1,3-BENZOTHIADIAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
5-METHYL-2,1,3-BENZOTHIADIAZOLE Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- +86 943-8535351 13389336721
- Fax
- +86-943-8535351
- sales@chengzechem.com
- Country
- China
- ProdList
- 289
- Advantage
- 58
- Tel
- 13598610367 0373-7129549
- Fax
- 0373-8369699
- 2468833170@qq.com
- Country
- China
- ProdList
- 932
- Advantage
- 58
- Tel
- 021-31261262/ 49 (0)17662837245
- Fax
- (0)21-33250524
- sales@novochemy.com
- Country
- Germany
- ProdList
- 6328
- Advantage
- 58
- Tel
- 021-11111111 11111111111
- Fax
- qq:546919421
- 546919421@qq.com
- Country
- China
- ProdList
- 3519
- Advantage
- 55
- Tel
- 0371-88888888 272369594
- Fax
- QQ:272369594
- 2723695949@qq.com
- Country
- China
- ProdList
- 4962
- Advantage
- 50
- Tel
- 0519-85528066 13775048983
- Fax
- 0519-85528066
- sales@hopschem.com
- Country
- China
- ProdList
- 31553
- Advantage
- 55
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 0371-55051623 18137891487
- Fax
- QQ：2853979817
- 2853979817@qq.com
- Country
- China
- ProdList
- 9999
- Advantage
- 58