HO-PEG8-CH2COOH

Product Name: HO-PEG8-CH2COOH
CAS No.: 780006-30-6
Chemical Name: HO-PEG8-CH2COOH
Synonyms: HO-PEG8-CH2COOH;Acetic acid, 2-[(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]-;HO-PEG8-CH2COOH/Acetic acid, 2-[(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]-
CBNumber: CB03309429
Molecular Formula: C18H36O11
Formula Weight: 428.47
MOL File: 780006-30-6.mol

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HO-PEG8-CH2COOH Property

Boiling point:: 543.7±45.0 °C(Predicted)
Density: 1.162±0.06 g/cm3(Predicted)
pka: 3.39±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Acrotein

Product number: B-0938
Product name: HO-PEG8-CH2COOH
Purity: 97%
Packaging: 1g
Price: $641.66
Updated: 2021/12/16

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HO-PEG8-CH2COOH Chemical Properties,Usage,Production

Biological Activity

HO-PEG8-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

HO-PEG8-CH2COOH Preparation Products And Raw materials

Raw materials

Preparation Products

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HO-PEG8-CH2COOH Suppliers

China 8 United States 3 Global 11

Amatek Scientific Co. Ltd.

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9i LLC

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780006-30-6, HO-PEG8-CH2COOHRelated Search:

HO-PEG8-CH2COOH

HO-PEG8-CH2COOH/Acetic acid, 2-[(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]-

Acetic acid, 2-[(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]-

780006-30-6