Leniolisib

ChemicalBook > CAS DataBase List > Leniolisib

Product Name: Leniolisib
CAS No.: 1354690-24-6
Chemical Name: Leniolisib
Synonyms: CS-2818;CDZ 173;Leniolisib;leniolisib(CDZ 173);CDZ173;CDZ-173;CDZ 173;Rupatadine Impurity 2-d8;inhibit,Inhibitor,Phosphoinositide 3-kinase,Leniolisib,PI3K,CDZ-173,CDZ 173;(S)-1-(3-((6-(6-Methoxy-5-(trifluoromethyl)pyridin-3-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)amino)pyrrolidin-1-yl)propan-1-one;1-Propanone, 1-[(3S)-3-[[5,6,7,8-tetrahydro-6-[6-methoxy-5-(trifluoromethyl)-3-pyridinyl]pyrido[4,3-d]pyrimidin-4-yl]amino]-1-pyrrolidinyl]-
CBNumber: CB03311734
Molecular Formula: C21H25F3N6O2
Formula Weight: 450.46
MOL File: 1354690-24-6.mol

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Leniolisib Property

storage temp.: Store at -20°C
solubility: DMF:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.11(Max Conc. mM)
DMSO:71.67(Max Conc. mg/mL);159.09(Max Conc. mM)
Ethanol:16.5(Max Conc. mg/mL);36.63(Max Conc. mM)
form: A crystalline solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28078
Product name: Leniolisib
Packaging: 1mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 28078
Product name: Leniolisib
Packaging: 25mg
Price: $770
Updated: 2024/03/01

Cayman Chemical

Product number: 28078
Product name: Leniolisib
Packaging: 5mg
Price: $227
Updated: 2024/03/01

Cayman Chemical

Product number: 28078
Product name: Leniolisib
Packaging: 10mg
Price: $403
Updated: 2024/03/01

ChemScene

Product number: CS-7524
Product name: Leniolisib
Purity: 99.25%
Packaging: 10mg
Price: $350
Updated: 2021/12/16

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Leniolisib Chemical Properties,Usage,Production

Biological Activity

Leniolisib (CDZ 173) is a potent and selective PI3Kδ inhibitor with IC50s of 0.244, 0.424, 2.23 and 0.011 μM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively.

target

< td style="border-bottom: 1px dotted #ccc;padding: 5px;"> PI3Kβ
(Cell-free assay)

Target	Value
PI3Kδ (Cell-free assay)	0.011 μM
PI3Kα (Cell-free assay)	0.244 μM
0.424 μM
DNA-PK ()	0.88 μM
DNA-PK (Cell-free assay)	0.88 μM

Leniolisib Preparation Products And Raw materials

Raw materials

Preparation Products

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1354690-24-6, LeniolisibRelated Search:

Leniolisib

CDZ173;CDZ-173;CDZ 173

CS-2818

leniolisib(CDZ 173)

CDZ 173

1-Propanone, 1-[(3S)-3-[[5,6,7,8-tetrahydro-6-[6-methoxy-5-(trifluoromethyl)-3-pyridinyl]pyrido[4,3-d]pyrimidin-4-yl]amino]-1-pyrrolidinyl]-

(S)-1-(3-((6-(6-Methoxy-5-(trifluoromethyl)pyridin-3-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)amino)pyrrolidin-1-yl)propan-1-one

inhibit,Inhibitor,Phosphoinositide 3-kinase,Leniolisib,PI3K,CDZ-173,CDZ 173

Rupatadine Impurity 2-d8

1354690-24-6

C21H25F3N6O2