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2-(3-sulfanylpropyl)pentanedioic acid

Product Name
2-(3-sulfanylpropyl)pentanedioic acid
CAS No.
254737-29-6
Chemical Name
2-(3-sulfanylpropyl)pentanedioic acid
Synonyms
2-MPPA;2MPPA,2 MPPA;FNLNSQHJKVQCBP-UHFFFAOYSA-N;2-(3-Mercaptopropyl)pentanedioic acid;2-(3-sulfanylpropyl)pentanedioic acid;Pentanedioic acid, 2-(3-mercaptopropyl)-
CBNumber
CB03313172
Molecular Formula
C8H14O4S
Formula Weight
206.26
MOL File
254737-29-6.mol
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2-(3-sulfanylpropyl)pentanedioic acid Property

Melting point:
51-53 °C
Boiling point:
377.124±32.00 °C(Press: 760.00 Torr)(predicted)
Density 
1.256±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. 
Store at -20°C
solubility 
Soluble to 100 mM in water and to 100 mM in DMSO
form 
Powder
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ApexBio Technology
Product number
B7734
Product name
2-MPPA
Packaging
10mg
Price
$285
Updated
2026/05/06
ACHEMBLOCK
Product number
AD268626
Product name
2-MPPA
Purity
98%
Packaging
5MG
Price
$125
Updated
2026/05/27
ACHEMBLOCK
Product number
AD268626
Product name
2-MPPA
Purity
98%
Packaging
25MG
Price
$375
Updated
2026/05/27
ACHEMBLOCK
Product number
AD268626
Product name
2-MPPA
Purity
98%
Packaging
100MG
Price
$715
Updated
2026/05/27
Arctom
Product number
HY-103345
Product name
2-MPPA
Purity
98.0%
Packaging
5mg
Price
$124
Updated
2026/05/26
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2-(3-sulfanylpropyl)pentanedioic acid Chemical Properties,Usage,Production

Uses

2-MPPA is a selective glutamate carboxypeptidase II (GCP-II) inhibitor used in the treatment of neurological disorders associated with excessive activation of glutamatergic systems. Attenuates glutamate transmission resulting in the relief of neuropathic pain. This compound has neuroprotective properties.

in vivo

2-MPPA (10, 30 or 100 mg/kg) significantly attenuates Dizocilpine (HY-15084B) (0.1 mg/kg)-induced prepulse inhibition (PPI) deficits in mice, in a dose dependent manner. The efficacy of 2-MPPA on dizocilpine-induced PPI deficits is significantly antagonized by pretreatment with the selective group II metabotropic glutamate receptor (mGluR) antagonist LY341495 (HY-70059) (1.0 mg/kg)[1].
2-MPPA (30 mg/kg) significantly prevents the deficit in SNCV induced by both 5 and 25 mg/kg taxol by 96.3 ± 4.4% and 98.3± 11.6% respectively[2].
2-MPPA (10 mg/kg) inhibits tumor growth in the high expressor PSMA model CWR22RS by 70%[2].

2-(3-sulfanylpropyl)pentanedioic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(3-sulfanylpropyl)pentanedioic acid Suppliers

Hangzhou ChangCun Biotechnology Co., Ltd.
Tel
0571-; 13567100326
Fax
QQ158848739
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158848739@qq.com
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China
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Shanghai Chaolan Chemical Technology Center
Tel
QQ:65489617 19372819560
Fax
21-5161 9052
Email
Sales@ATKchemical.com
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China
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TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32466
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Hunan Huayi Zhide Pharmaceutical Technology Co., Ltd.
Tel
17752881701
Email
190060276@qq.com
Country
China
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MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
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China
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Energy Chemical
Tel
021-58432009 400-005-6266
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Nantong Hi-Future Biotechnology Co., Ltd
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China
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TargetMol Chemicals Inc.
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marketing@tsbiochem.com
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China
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Suzhou Meishi Biotechnology Co., Ltd.
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meishipharma@126.com
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China
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Shanghai Tachizaki Biomedical Research Center
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18014399201
Email
sales@chemlab-tachizaki.com
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China
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254737-29-6, 2-(3-sulfanylpropyl)pentanedioic acidRelated Search:


  • 2-(3-sulfanylpropyl)pentanedioic acid
  • FNLNSQHJKVQCBP-UHFFFAOYSA-N
  • 2-(3-Mercaptopropyl)pentanedioic acid
  • 2-MPPA
  • Pentanedioic acid, 2-(3-mercaptopropyl)-
  • 2MPPA,2 MPPA
  • 254737-29-6