2-(3-sulfanylpropyl)pentanedioic acid

Product Name: 2-(3-sulfanylpropyl)pentanedioic acid
CAS No.: 254737-29-6
Chemical Name: 2-(3-sulfanylpropyl)pentanedioic acid
Synonyms: 2-MPPA;2MPPA,2 MPPA;FNLNSQHJKVQCBP-UHFFFAOYSA-N;2-(3-Mercaptopropyl)pentanedioic acid;2-(3-sulfanylpropyl)pentanedioic acid;Pentanedioic acid, 2-(3-mercaptopropyl)-
CBNumber: CB03313172
Molecular Formula: C8H14O4S
Formula Weight: 206.26
MOL File: 254737-29-6.mol

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2-(3-sulfanylpropyl)pentanedioic acid Property

Melting point:: 51-53 °C
Boiling point:: 377.124±32.00 °C(Press: 760.00 Torr)(predicted)
Density: 1.256±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp.: Store at -20°C
solubility: Soluble to 100 mM in water and to 100 mM in DMSO
form: Powder
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Tocris

Product number: 5033
Product name: 2-MPPA
Packaging: 10
Price: $202
Updated: 2021/12/16

Usbiological

Product number: 254369
Product name: 2-MPPA
Packaging: 10mg
Price: $522
Updated: 2021/12/16

TRC

Product number: M745810
Product name: 2-MPPA
Packaging: 100mg
Price: $1470
Updated: 2021/12/16

ApexBio Technology

Product number: B7734
Product name: 2-MPPA
Packaging: 10mg
Price: $345
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 71639
Product name: 2-MPPA
Packaging: 10mg
Price: $675
Updated: 2021/12/16

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2-(3-sulfanylpropyl)pentanedioic acid Chemical Properties,Usage,Production

Uses

2-MPPA is a selective glutamate carboxypeptidase II (GCP-II) inhibitor used in the treatment of neurological disorders associated with excessive activation of glutamatergic systems. Attenuates glutamate transmission resulting in the relief of neuropathic pain. This compound has neuroprotective properties.

in vivo

2-MPPA (10, 30 or 100 mg/kg) significantly attenuates Dizocilpine (HY-15084B) (0.1 mg/kg)-induced prepulse inhibition (PPI) deficits in mice, in a dose dependent manner. The efficacy of 2-MPPA on dizocilpine-induced PPI deficits is significantly antagonized by pretreatment with the selective group II metabotropic glutamate receptor (mGluR) antagonist LY341495 (HY-70059) (1.0 mg/kg)^[1].
2-MPPA (30 mg/kg) significantly prevents the deficit in SNCV induced by both 5 and 25 mg/kg taxol by 96.3 ± 4.4% and 98.3± 11.6% respectively^[2].
2-MPPA (10 mg/kg) inhibits tumor growth in the high expressor PSMA model CWR22RS by 70%^[2].

2-(3-sulfanylpropyl)pentanedioic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(3-sulfanylpropyl)pentanedioic acid Suppliers

China 27 India 1 United Kingdom 1 United States 3 USA 1 Global 33

Hangzhou ChangCun Biotechnology Co., Ltd.

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MedBioPharmaceutical Technology Inc

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Energy Chemical

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TargetMol Chemicals Inc.

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Suzhou Meishi Biotechnology Co., Ltd.

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Shanghai Tachizaki Biomedical Research Center

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254737-29-6, 2-(3-sulfanylpropyl)pentanedioic acidRelated Search:

2-(3-sulfanylpropyl)pentanedioic acid

FNLNSQHJKVQCBP-UHFFFAOYSA-N

2-(3-Mercaptopropyl)pentanedioic acid

2-MPPA

Pentanedioic acid, 2-(3-mercaptopropyl)-

2MPPA,2 MPPA

254737-29-6