BMS711939

Product Name: BMS711939
CAS No.: 1000998-62-8
Chemical Name: BMS711939
Synonyms: BMS711939;N-(5-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methoxy)-2-fluorobenzyl)-n-(methoxycarbonyl)glycine;Glycine, N-[[5-[[2-(4-chlorophenyl)-5-methyl-4-oxazolyl]methoxy]-2-fluorophenyl]methyl]-N-(methoxycarbonyl)-
CBNumber: CB03333709
Molecular Formula: C22H20ClFN2O6
Formula Weight: 462.86
MOL File: 1000998-62-8.mol

More

Less

BMS711939 Property

Boiling point:: 650.1±65.0 °C(Predicted)
Density: 1.379±0.06 g/cm3(Predicted)
pka: 3.90±0.10(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

BMS711939 Chemical Properties,Usage,Production

Uses

BMS711939 is a selective agonist for peroxisome proliferator-activated receptor α (PPAR α), with EC50 of 4 nM and 4.5 μM, for human PPARα and human PPARγ. BMS711939 exhibits good pharmacokinetic characters in rats models. BMS711939 increases HDL cholesterol, reduces LDL cholesterol and triglycerides[1].

IC 50

hPPARα: 4 nM (IC₅₀); hPPARγ: 4.5 μM (IC₅₀)

References

[1] Shi Y, et al., Discovery and Preclinical Evaluation of BMS-711939, an Oxybenzylglycine Based PPARα Selective Agonist. ACS Med Chem Lett. 2016 Apr 4;7(6):590-4. DOI:10.1021/acsmedchemlett.6b00033

BMS711939 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

BMS711939 Suppliers

China 4 United States 5 Global 9

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 12952
Advantage: 65

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Allbio pharm Co., Ltd

Tel: 1483287082 19962651230
Email: sales@allbiopharm.com
Country: China
ProdList: 1529
Advantage: 58

InvivoChem

Tel: 13549236410
Email: sales@invivochem.cn
Country: China
ProdList: 6753
Advantage: 58

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29257
Advantage: 58

TargetMol Chemicals Inc.

Tel: +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 19961
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354;
Email: support@targetmol.com
Country: United States
ProdList: 39035
Advantage: 58

Hangzhou MolCore BioPharmatech Co.,Ltd.

Tel: +86-057181025280; +8617767106207
Fax: 0571-85806285
Email: sales@molcore.com
Country: China
ProdList: 49734
Advantage: 58

1000998-62-8, BMS711939Related Search:

BMS711939

N-(5-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methoxy)-2-fluorobenzyl)-n-(methoxycarbonyl)glycine

Glycine, N-[[5-[[2-(4-chlorophenyl)-5-methyl-4-oxazolyl]methoxy]-2-fluorophenyl]methyl]-N-(methoxycarbonyl)-

1000998-62-8