3'-Azido-3'-deoxy-N6,N6-dimethyladenosine
- Product Name
- 3'-Azido-3'-deoxy-N6,N6-dimethyladenosine
- CAS No.
- 384334-64-9
- Chemical Name
- 3'-Azido-3'-deoxy-N6,N6-dimethyladenosine
- Synonyms
- 3'-Azido-3'-deoxy-N6-dimethyladenosine;3'-Azido-3'-deoxy-N6,N6-dimethyladenosine;3’-Azido-3’-deoxy-N6,N6-dimethyladenosine;4-azido-2-(6-(dimethylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3-ol
- CBNumber
- CB03334241
- Molecular Formula
- C12H16N8O3
- Formula Weight
- 320.31
- MOL File
- 384334-64-9.mol
3'-Azido-3'-deoxy-N6,N6-dimethyladenosine Chemical Properties,Usage,Production
Uses
3’-Azido-3’-deoxy-N6,N6-dimethyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 3’-Azido-3’-deoxy-N6,N6-dimethyladenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
3'-Azido-3'-deoxy-N6,N6-dimethyladenosine Preparation Products And Raw materials
Raw materials
Preparation Products
3'-Azido-3'-deoxy-N6,N6-dimethyladenosine Suppliers
- Tel
- 021-61551611 13296011611
- Fax
- +86 21-50676805
- contact@trustwe.com
- Country
- China
- ProdList
- 9895
- Advantage
- 58
- Tel
- 0371-85513397 +86-18610099868
- info@granlen.com
- Country
- China
- ProdList
- 1890
- Advantage
- 58
- Tel
- +86-0571-86912261 +8613735419629
- sales@newcanbio.com
- Country
- China
- ProdList
- 9985
- Advantage
- 58
- Tel
- 16314854226
- Fax
- 1-631-614-7828
- inquiry@bocsci.com
- Country
- United States
- ProdList
- 9713
- Advantage
- 58
- Tel
- +1-631-485-4226
- Fax
- 1-631-614-7828
- inquiry@bocsci.com
- Country
- United States
- ProdList
- 19552
- Advantage
- 58
- Tel
- +86-021-61551413 +8618813727289
- contact@trustwe.com
- Country
- China
- ProdList
- 5743
- Advantage
- 58
- Tel
- 15002134094
- marketing@targetmol.cn
- Country
- China
- ProdList
- 29358
- Advantage
- 58
- Tel
- 51288865780
- sales@biosynth.com
- Country
- China
- ProdList
- 6051
- Advantage
- 58
- Tel
- 021-68689288 15300790979
- Fax
- wechat 18721550091
- info@mkbio.com.cn
- Country
- China
- ProdList
- 5000
- Advantage
- 58
- Tel
- +86-16621589600
- contact@scibiotron.com
- Country
- China
- ProdList
- 5535
- Advantage
- 58