ChemicalBook > CAS DataBase List > 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil

1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil

Product Name
1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil
CAS No.
69123-94-0
Chemical Name
1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil
Synonyms
FAU;1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione;1-((2R,3S,4R,5R)-3-FLUORO-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-2-YL)-1H-PYRIMIDINE-2,4-DIONE;1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione;Ara-2'-F-2'-dU;2'-FANA-uridine;antiviral anticancer agent;2'-Fluoro-2'-deoxy-arabino-Uridine;2'-Deoxy-2'-fluoro--D-arabinouridine;2-Deoxy-2'-fluoro-β-D-arabinouridine
CBNumber
CB0333522
Molecular Formula
C9H11FN2O5
Formula Weight
246.19
MOL File
69123-94-0.mol
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1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil Property

Melting point:
162 °C(Solv: chloroform (67-66-3); methanol (67-56-1))
Density 
1.63±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Methanol: Soluble
pka
9.39±0.10(Predicted)
form 
Solid
color 
White to off-white
InChI
InChI=1/C9H11FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h1-2,4,6-8,13,15H,3H2,(H,11,14,16)/t4-,6+,7-,8-/s3
InChIKey
UIYWFOZZIZEEKJ-QOUWCGOQNA-N
SMILES
[C@@H]1([C@@H](F)[C@H](O)[C@@H](CO)O1)N1C=CC(=O)NC1=O |&1:0,1,3,5,r|
CAS DataBase Reference
69123-94-0
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Safety

HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H340May cause genetic defects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

TRC
Product number
D239968
Product name
1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)uracil
Packaging
500mg
Price
$90
Updated
2021/12/16
Apolloscientific
Product number
PC56119
Product name
2'-Fluoro-2'-deoxy-β-D-arabino-furanosyluridine
Packaging
1g
Price
$93
Updated
2021/12/16
Biosynth Carbosynth
Product number
ND06062
Product name
1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)uracil
Packaging
2g
Price
$110
Updated
2021/12/16
AK Scientific
Product number
0661AC
Product name
1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)uracil
Packaging
2g
Price
$198
Updated
2021/12/16
Biosynth Carbosynth
Product number
ND06062
Product name
1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)uracil
Packaging
5G
Price
$250
Updated
2021/12/16
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1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil Chemical Properties,Usage,Production

Chemical Properties

Colourless solid

Uses

1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] KYOICHI A. WATANABE. Nucleosides. 110. Synthesis and antiherpes virus activity of some 2’-fluoro-2’-deoxyarabinofuranosylpyrimidine nucleosides[J]. Journal of Medicinal Chemistry, 1979, 22 1: 21-24. DOI: 10.1021/jm00187a005

1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil 69123-94-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-29
Career Henan Chemical Co
Product
1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil 69123-94-0
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1tons
Release date
2018-08-08

69123-94-0, 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracilRelated Search:

CHLOROPHOSPHONAZO III Furazolidone Floxuridine Tetrahydrofuran Uracil Tris(hydroxymethyl)nitromethane Pyrimidine FURFURYL ALCOHOL RESIN Carbofuran Fialuridine Hydroxymethyl 2',2'-DIFLUORO-2'-DEOXYURIDINE 5-Trimethylstannyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil 2',2'-DIFLUORO-2'-DEOXYURIDINE 13C, 15N2 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil 2'-FLUORO-2'-DEOXYARABINOFURANOSYL-URACIL, [5-3H]- 2'-FLUORO 2'-DEOXYURACIL-BETA-D-ARABINOFURANOSIDE, [2-14C]- 2'-FLUORO 2'-DEOXYURACIL-BETA-D-ARABINOFURANOSIDE, 5'-MONOPHOSPHATE, DITRIETHYLAMMONIUM SALT, [5-3H]-

  • 2’-fluoro-5-ethyl-1-beta-d-arabinofuranosyluracil
  • 1,3-Dimethyl-4-Amino-5-Formamide-Uracil FAU
  • 1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)uracil
  • 1-[(2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
  • 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-
  • 2'-Fluoro-arabinofuranosyl-2'-deoxy-uridine
  • 2'-Deoxy-2'-fluoro-beta-D-arabinouridine
  • 2,4(1H,3H)-PyriMidinedione, 1-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-
  • 1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
  • 2'-Fluoro-2'-deoxy-arabinofuranosyl-uridine
  • 2,4(1H,3H)-PYRIMIDINEDIONE, 1-(2-DEOXY-2-FLUORO-BETA-D-ARABINOFURANOSYL)
  • 2'-FLUORO 2'-DEOXYURACIL-BETA-D-ARABINOFURANOSIDE
  • 2'-FLUORO-2'-DEOXYURACYL-BETA-D-ARABINOFURANOSIDE
  • 1-(2-DEOXY-2-FLUORO-BETA-D-ARABINOFURANOSYL)URACIL
  • 1-((2R,3S,4R,5R)-3-FLUORO-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-2-YL)-1H-PYRIMIDINE-2,4-DIONE
  • FAU
  • 1-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)-uraci
  • 2'-Deoxy-2'-fluoro--D-arabinouridine
  • 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
  • Ara-2'-F-2'-dU
  • 2'-Fluoro-2'-deoxy-β-D-arabino-furanosyluridine
  • 2’-Deoxy-2’-fluoro-β-D-arabinouridine
  • 2'-Fluoro-2'-deoxy-arabino-Uridine
  • 2'-Fluoro-2'-deoxy-β-Darabino-furanosyluridine
  • 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)uracil
  • 2’-Deoxy-2’-fluoro-b-D-arabinouridine, antiviral anticancer agent
  • 2’-Deoxy-2’-fluoro-b-D-arabinouridine
  • antiviral anticancer agent
  • 2’-Deoxy-2’-fluoro-beta-D-arabinouridine
  • 2'-FANA-uridine
  • 2-Deoxy-2'-fluoro-β-D-arabinouridine
  • 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil - [D92724]
  • 69123-94-0
  • Nucleosides-2'-FANA Nucleosides