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(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone

Product Name
(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone
CAS No.
152831-00-0
Chemical Name
(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone
Synonyms
Benzbromarone Impurity 10;BenzbromaroneImpurity7-13C6;BenzbromaroneImpurity7-13C3-d2;Benzbromarone 6-Hydroxy Impurity;Benzbromarone Impurity 7 (6-Hydroxy-Benzbromarone);Benzbromarone Impurity 10 (6-Hydroxy-Benzbromarone）;(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone;METHANONE,(3,5-DIBROMO-4-HYDROXYPHENYL)(2-ETHYL-6-HYDROXY-3-BENZOFURANYL)-
CBNumber
CB03340079
Molecular Formula
C17H12Br2O4
Formula Weight
440.08
MOL File
152831-00-0.mol
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(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone Property

Boiling point:
444.9±45.0 °C(Predicted)
Density 
1.785±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
pka
4.53±0.25(Predicted)
form 
Solid
color 
Off-white to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
H949713
Product name
6-Hydroxybenzbromarone
Packaging
25mg
Price
$2090
Updated
2021/12/16
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(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone Chemical Properties,Usage,Production

Uses

6-Hydroxybenzbromarone is an angiogenic agent with potent inhibitory effects on cell migration, tubulogenesis and angiogenesis.

Biological Activity

6-Hydroxybenzbromarone is the main metabolite of Benzbromarone, which has a longer half-life and greater pharmacological potency than the parent compound. 6-Hydroxybenzbromarone is an EYA3 inhibitor with IC50 of 21.5 μM.

target

IC50: 21.5 μM (EYA3); metabolite

(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone Preparation Products And Raw materials

Raw materials

Preparation Products

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(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone Suppliers

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TargetMol Chemicals Inc.
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152831-00-0, (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanoneRelated Search:

2-Ethylbenzofuran 3,5-dibromo-4-hydroxyBenzoyl chloride (6-BroMo-2-ethyl-3-benzofuranyl)(3,5-dibroMo-4-hydroxyphenyl)Methanone Benzobromoma impurity 1 bromobenzarone 3,5-Dibromo-4-hydroxybenzoic acid Benzobromoma impurity 4 Benzbromarone Benzobromoma impurity 3 Benzbromarone Impurity 3 Benzbromarone D5 Benzobromoma impurity 2

  • Benzbromarone Impurity 7 (6-Hydroxy-Benzbromarone)
  • (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone
  • METHANONE,(3,5-DIBROMO-4-HYDROXYPHENYL)(2-ETHYL-6-HYDROXY-3-BENZOFURANYL)-
  • Benzbromarone 6-Hydroxy Impurity
  • Benzbromarone Impurity 10 (6-Hydroxy-Benzbromarone）
  • Benzbromarone Impurity 10
  • BenzbromaroneImpurity7-13C6
  • BenzbromaroneImpurity7-13C3-d2
  • 152831-00-0