(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID

Product Name: (E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID
CAS No.: 127910-31-0
Chemical Name: (E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID
Synonyms: CGP 37849;CGP 37849;CGP-37849;CGP37849;dl-2-amino-4-methyl-5-phosphono-3-*pentenoic acid;(E)-2-Amino-4-methyl-5-phosphonopent-3-enoic acid;(3E)-2-Amino-4-methyl-5-phosphono-3-pentanoic acid;(E)-(±)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID;3-Pentenoic acid, 2-amino-4-methyl-5-phosphono-, (3E)-;(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID
CBNumber: CB0334453
Molecular Formula: C6H12NO5P
Formula Weight: 209.14
MOL File: 127910-31-0.mol

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(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID Property

Boiling point:: 523.1±60.0 °C(Predicted)
Density: 1.506±0.06 g/cm3(Predicted)
storage temp.: Desiccate at +4°C
solubility: H2O: ≥2mg/mL (warmed)
form: powder
pka: 1.83±0.10(Predicted)
color: white to beige

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0050
Product name: CGP 37849
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $100
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0050
Product name: CGP 37849
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $500
Updated: 2024/03/01

Tocris

Product number: 1469
Product name: CGP 37849
Purity: ≥99%(HPLC)
Packaging: 50
Price: $649
Updated: 2021/12/16

Tocris

Product number: 1469
Product name: CGP 37849
Purity: ≥99%(HPLC)
Packaging: 10
Price: $156
Updated: 2021/12/16

TRC

Product number: C583545
Product name: CGP 37849
Packaging: 25mg
Price: $305
Updated: 2021/12/16

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(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID Chemical Properties,Usage,Production

Uses

CGP 37849 is a potent antagonist at NMDA receptors which results in anticonvulsant activity (1). In addition, it may antagonize NMDA-antagonistic induced antianxiety effects (2).

Biological Activity

Potent, selective and competitive NMDA receptor antagonist (K i = 35 nM). Anticonvulsive following oral administration in vivo .

storage

Desiccate at +4°C

(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID Suppliers

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127910-31-0, (E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACIDRelated Search:

(2R,3E)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid 2-amino-4-methyl-5-phosphono-3-pentenoic acid (2R,3E)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid 1-ethyl ester (2S,3E)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid (2S,3E)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid 1-ethyl ester 2-AMINO-3-BUTENOIC ACID ALLYLPHOSPHONIC ACID CGP 39653, [PROPYL-2,3,3H]- (E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID (E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID ETHYL ESTER,(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID ETHYLESTHER

dl-2-amino-4-methyl-5-phosphono-3-*pentenoic acid

(3E)-2-Amino-4-methyl-5-phosphono-3-pentanoic acid

(E)-2-Amino-4-methyl-5-phosphonopent-3-enoic acid

(E)-(±)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID

CGP 37849

(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID

CGP 37849;CGP-37849;CGP37849

3-Pentenoic acid, 2-amino-4-methyl-5-phosphono-, (3E)-

127910-31-0

C6H12NO5P

Glutamate receptor

Glutamate