ChemicalBook > CAS DataBase List > 1-(4-(tert-butyl)benzyl)-3-(4-chlorophenyl)-N-hydroxy-1H-pyrazole-5-carboxamide

1-(4-(tert-butyl)benzyl)-3-(4-chlorophenyl)-N-hydroxy-1H-pyrazole-5-carboxamide

Product Name
1-(4-(tert-butyl)benzyl)-3-(4-chlorophenyl)-N-hydroxy-1H-pyrazole-5-carboxamide
CAS No.
1610022-76-8
Chemical Name
1-(4-(tert-butyl)benzyl)-3-(4-chlorophenyl)-N-hydroxy-1H-pyrazole-5-carboxamide
Synonyms
Nrf2 inhibitor 1;Nrf2-IN-1, 10 mM in DMSO;1-(4-(tert-butyl)benzyl)-3-(4-chlorophenyl);1-(4-(tert-butyl)benzyl)-3-(4-chlorophenyl)-N-hydroxy-1H-pyrazole-5-carboxamide;inhibit,Acute,leukemia,AML,myeloid,Nrf2,Inhibitor,Nrf2IN1,Keap1-Nrf2,Nrf-2-IN-1,Nrf2 IN 1;3-(4-Chlorophenyl)-1-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-hydroxy-1H-pyrazole-5-carboxamide;1H-Pyrazole-5-carboxamide, 3-(4-chlorophenyl)-1-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-hydroxy-
CBNumber
CB03353619
Molecular Formula
C21H22ClN3O2
Formula Weight
383.87
MOL File
1610022-76-8.mol
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1-(4-(tert-butyl)benzyl)-3-(4-chlorophenyl)-N-hydroxy-1H-pyrazole-5-carboxamide Property

Density 
1.23±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 260 mg/mL (677.31 mM)
form 
Solid
pka
8.44±0.50(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0020733
Product name
Nrf2-IN-1
Purity
98.90%
Packaging
5mg
Price
$350
Updated
2021/12/16
ChemScene
Product number
CS-0020733
Product name
Nrf2-IN-1
Purity
98.90%
Packaging
10mg
Price
$550
Updated
2021/12/16
ChemScene
Product number
CS-0020733
Product name
Nrf2-IN-1
Purity
98.90%
Packaging
50mg
Price
$1650
Updated
2021/12/16
ChemScene
Product number
CS-0020733
Product name
Nrf2-IN-1
Purity
98.90%
Packaging
100mg
Price
$2650
Updated
2021/12/16
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1-(4-(tert-butyl)benzyl)-3-(4-chlorophenyl)-N-hydroxy-1H-pyrazole-5-carboxamide Chemical Properties,Usage,Production

Biological Activity

Nrf2-IN-1 is an inhibitor of Nrf2 used in acute myeloid leukemia (AML) drug research.

in vivo

Nrf2-IN-1 inhibits tumor growth via apoptosis in chicken eggs.

target

Nrf2

1-(4-(tert-butyl)benzyl)-3-(4-chlorophenyl)-N-hydroxy-1H-pyrazole-5-carboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(4-(tert-butyl)benzyl)-3-(4-chlorophenyl)-N-hydroxy-1H-pyrazole-5-carboxamide Suppliers

Shanghai Aocheng Biological Technology Co., Ltd.
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13917627064
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China
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1610022-76-8, 1-(4-(tert-butyl)benzyl)-3-(4-chlorophenyl)-N-hydroxy-1H-pyrazole-5-carboxamideRelated Search:


  • 1-(4-(tert-butyl)benzyl)-3-(4-chlorophenyl)-N-hydroxy-1H-pyrazole-5-carboxamide
  • 1-(4-(tert-butyl)benzyl)-3-(4-chlorophenyl)
  • 3-(4-Chlorophenyl)-1-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-hydroxy-1H-pyrazole-5-carboxamide
  • Nrf2 inhibitor 1
  • 1H-Pyrazole-5-carboxamide, 3-(4-chlorophenyl)-1-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-hydroxy-
  • inhibit,Acute,leukemia,AML,myeloid,Nrf2,Inhibitor,Nrf2IN1,Keap1-Nrf2,Nrf-2-IN-1,Nrf2 IN 1
  • Nrf2-IN-1, 10 mM in DMSO
  • 1610022-76-8