AFG206

Product Name: AFG206
CAS No.: 630122-37-1
Chemical Name: AFG206
Synonyms: AFG206;Urea, N-(4-ethylphenyl)-N'-[4-(4-pyridinyloxy)phenyl]-
CBNumber: CB03358856
Molecular Formula: C20H19N3O2
Formula Weight: 333.38
MOL File: 630122-37-1.mol

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Hazard and Precautionary Statements (GHS)

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AFG206 Chemical Properties,Usage,Production

Description

AFG206 is the novel first-generation "type II" FLT3 inhibitor.

Uses

AFG206 is a first-generation ATP competitive “type II” FLT3 inhibitor. AFG206 potently inhibits cell proliferation (IC50 around 0.1 μM) via induction of Apoptosis in FLT3-ITD-Ba/F3 cells and D835Y-Ba/F3 cells. AFG206 is promising for research of acute myeloid leukemia[1].

References

[1] Weisberg E, et al. Antileukemic Effects of Novel First- and Second-Generation FLT3 Inhibitors: Structure-Affinity Comparison. Genes Cancer. 2010 Oct;1(10):1021-32. DOI:10.1177/1947601910396505

AFG206 Preparation Products And Raw materials

Raw materials

Preparation Products

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AFG206 Suppliers

China 2 United States 2 Global 4

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 12952
Advantage: 65

TargetMol Chemicals Inc.

Tel: +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 19961
Advantage: 58

630122-37-1, AFG206Related Search:

AFG206

Urea, N-(4-ethylphenyl)-N'-[4-(4-pyridinyloxy)phenyl]-

630122-37-1