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m-PEG5-Ms

Product Name
m-PEG5-Ms
CAS No.
130955-37-2
Chemical Name
m-PEG5-Ms
Synonyms
PEG4-Oms;m-PEG5-Ms;m-PEG4-OMs;2,5,8,11-Tetraoxatridecan-13-yl methanesulfonate;2,5,8,11-Tetraoxatridecan-13-ol, 13-methanesulfonate
CBNumber
CB03363955
Molecular Formula
C10H22O7S
Formula Weight
286.34
MOL File
130955-37-2.mol
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m-PEG5-Ms Property

storage temp. 
Storage temp. 2-8°C
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23516
Product name
m-PEG5-Ms
Purity
98%
Packaging
500mg
Price
$180
Updated
2021/12/16
BroadPharm
Product number
BP-23516
Product name
m-PEG5-Ms
Purity
98%
Packaging
1g
Price
$330
Updated
2021/12/16
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m-PEG5-Ms Chemical Properties,Usage,Production

Description

m-PEG5-Ms is a PEG linker containing a mesyl group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

m-PEG4-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Biological Activity

m-PEG4-Ms is a PROTAC bridge and belongs to the PEG class. m-PEG4-Ms can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC bridge for the synthesis of antibody drug conjugates (ADCs).

target

IC 50

Cleavable Linker; PEGs

References

[1] Sanxing Sun, et al. Triazolotriazine derivatives as a2a receptor antagonists. WO2020002969A1.

m-PEG5-Ms Preparation Products And Raw materials

Raw materials

Preparation Products

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m-PEG5-Ms Suppliers

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Cleavable

PEGs