JPH203 HCl
- Product Name
- JPH203 HCl
- CAS No.
- 1597402-27-1
- Chemical Name
- JPH203 HCl
- Synonyms
- JPH203 HCl;JPH203 HCI;nanvuranlat;JPH203 2HCl;JPH203 Dihydrochloride;JPH203 (hydrochloride);KYT-0353 dihydrochloride;Nanvuranlat DiHCl (JPH203 DiHCl);JPH203 dihydrochloride, 10 mM in DMSO;JPH-203 dihydrochloride,JPH203 dihydrochloride
- CBNumber
- CB03372173
- Molecular Formula
- C23H20Cl3N3O4
- Formula Weight
- 508.78
- MOL File
- 1597402-27-1.mol
JPH203 HCl Property
- storage temp.
- Store at -20°C
- solubility
- DMSO:54.52(Max Conc. mg/mL);100.0(Max Conc. mM)
- form
- A solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- DC31420
- Product name
- JPH203dihydrochloride
- Packaging
- 100mg
- Price
- $550
- Updated
- 2021/12/16
- Product number
- DC31420
- Product name
- JPH203dihydrochloride
- Packaging
- 250mg
- Price
- $950
- Updated
- 2021/12/16
- Product number
- DC31420
- Product name
- JPH203dihydrochloride
- Packaging
- 1g
- Price
- $1900
- Updated
- 2021/12/16
JPH203 HCl Chemical Properties,Usage,Production
Description
JPH203 is an inhibitor of L-type amino acid transporter 1 (LAT1; IC50 = 0.14 μM for 14C-leucine uptake in S2 cells expressing the human transporter).1 It is selective for LAT1 over LAT2 (IC50 = >10 μM). JPH203 inhibits 14C-leucine uptake by, and growth of, HT-29 cells (IC50s = 0.06 and 4.1 μM, respectively). It induces apoptosis and increases levels of cleaved caspase-3, caspase-7, caspase-9, and poly(ADP-ribose) polymerase (PARP) in YD-38 oral cancer cells when used at a concentration of 3 mM.2 JPH203 (6.3, 12.5, and 25 mg/kg) reduces tumor growth in an HT-29 mouse xenograft model.1WARNING This product is not for human or veterinary use.
storage
Store at -20°C
JPH203 HCl Preparation Products And Raw materials
Raw materials
Preparation Products
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