N-(Azido-PEG2)-N-Boc-PEG3-NHS ester

Product Name: N-(Azido-PEG2)-N-Boc-PEG3-NHS ester
CAS No.: 2093153-85-4
Chemical Name: N-(Azido-PEG2)-N-Boc-PEG3-NHS ester
Synonyms: LUN 53854;N-(Azido-PEG2)-N-Boc-PEG3-NHS ester;2,5-Dioxopyrrolidin-1-yl 1-azido-9-(tert-butoxycarbonyl)-3,6,12,15,18-pentaoxa-9-azahenicosan-21-oate
CBNumber: CB03373680
Molecular Formula: C24H41N5O11
Formula Weight: 575.60924
MOL File: 2093153-85-4.mol

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N-(Azido-PEG2)-N-Boc-PEG3-NHS ester Property

storage temp.: Storage temp. -20°C
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23518
Product name: N-(Azido-PEG2)-N-Boc-PEG3-NHSester
Purity: 98%
Packaging: 100mg
Price: $320
Updated: 2021/12/16

BroadPharm

Product number: BP-23518
Product name: N-(Azido-PEG2)-N-Boc-PEG3-NHSester
Purity: 98%
Packaging: 250mg
Price: $650
Updated: 2021/12/16

BroadPharm

Product number: BP-23518
Product name: N-(Azido-PEG2)-N-Boc-PEG3-NHSester
Purity: 98%
Packaging: 500mg
Price: $980
Updated: 2021/12/16

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N-(Azido-PEG2)-N-Boc-PEG3-NHS ester Chemical Properties,Usage,Production

Description

N-(Azido-PEG2)-N-Boc-PEG3-NHS ester is a developed as branched labeling reagent. The azide group enables PEGylation via Click Chemistry. The protected amine can be deprotected under acidic conditions. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Uses

N-(Azido-PEG2)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azido-PEG2)-N-Boc-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N-(Azido-PEG2)-N-Boc-PEG3-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(Azido-PEG2)-N-Boc-PEG3-NHS ester Suppliers

China 19 United States 3 Global 22

Bide Pharmatech Ltd.

Tel: 400-400-164-7117 18317119277
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 40000
Advantage: 60

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-80534353 19917294565
Email: et@chemextension.com
Country: China
ProdList: 3828
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Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4952
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32467
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Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
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Zhengzhou Akem Chemical Co., Ltd

Tel: 13303867194
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Country: China
ProdList: 9800
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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
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Affinity（Wuhan）Ltd.

Tel: 15841022315
Email: sales@affinitytech.cn
Country: China
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TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24960
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Henan Alpha Chemical Co., Ltd.

Tel: 0371-55013243 15324716602
Email: 2232176231@qq.com
Country: China
ProdList: 9997
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View Lastest Price from N-(Azido-PEG2)-N-Boc-PEG3-NHS ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: N-(Azido-PEG2)-N-Boc-PEG3-NHS ester 2093153-85-4
Price: US $0.00/mg
Min. Order: 500mg
Purity: >95.00%
Supply Ability: 500mg
Release date: 2024-03-28

2093153-85-4, N-(Azido-PEG2)-N-Boc-PEG3-NHS esterRelated Search:

N-(Azido-PEG2)-N-Boc-PEG3-NHS ester

LUN 53854

2,5-Dioxopyrrolidin-1-yl 1-azido-9-(tert-butoxycarbonyl)-3,6,12,15,18-pentaoxa-9-azahenicosan-21-oate

2093153-85-4