1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride

ChemicalBook > CAS DataBase List > 1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride

Product Name: 1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride
CAS No.: 1620278-72-9
Chemical Name: 1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride
Synonyms: TLR7/8 agonist-5d;TLR7/8 agonist 1 2HCl;8 agonist 1 dihydrochloride;TLR7/8 Agonist 1 (hydrochloride);TLR7/8 Agonist 5d (hydrochloride);TLR7/8 agonist 1 (dihydrochloride);1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride;Toll-like Receptor (TLR),TLR7/8 agonist 1,TLR7/8 agonist 1 dihydrochloride,TLR-7/8 agonist 1 dihydrochloride,Inhibitor,inhibit
CBNumber: CB03374339
Molecular Formula: C22H26ClN5
Formula Weight: 395.94
MOL File: 1620278-72-9.mol

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1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride Property

storage temp.: Store at -20°C
solubility: DMSO:83.33(Max Conc. mg/mL);192.72(Max Conc. mM)
form: A solid

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28451
Product name: TLR7/8 Agonist 1 (hydrochloride)
Packaging: 500μg
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 28451
Product name: TLR7/8 Agonist 1 (hydrochloride)
Packaging: 5mg
Price: $468
Updated: 2024/03/01

Cayman Chemical

Product number: 28451
Product name: TLR7/8 Agonist 1 (hydrochloride)
Packaging: 1mg
Price: $131
Updated: 2024/03/01

AK Scientific

Product number: 3353EB
Product name: TLR7/8agonist1(dihydrochloride)
Packaging: 1mg
Price: $243
Updated: 2021/12/16

ChemScene

Product number: CS-0032947
Product name: TLR7/8agonist1(dihydrochloride)
Purity: 98.47%
Packaging: 10mg
Price: $550
Updated: 2021/12/16

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1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride Chemical Properties,Usage,Production

Biological Activity

TLR7/8 agonist 1 dihydrochloride is a dual agonist of the toll-like receptor TLR7/TLR8.

in vitro

TLR7/8 agonist 1 (Compound 5d) shows prominent immunostimulatory activities. TLR7/8 agonist 1 serves as a convenient precursor for the covalent attachment of fluorophores without significant loss of activity.It retains TLR7- agonistic activity with an EC ₅₀ of 20 nM. TLR7/8 agonist 1 (Compound 1) shows substantially different agonistic potencies in human TLR7 (50 nM) and TLR8 (55 nM) primary screens.

target

TLR7/TLR8

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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1620278-72-9, 1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochlorideRelated Search:

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride

TLR7/8 agonist 1 (dihydrochloride)

TLR7/8 agonist-5d

TLR7/8 Agonist 1 (hydrochloride)

8 agonist 1 dihydrochloride

TLR7/8 Agonist 5d (hydrochloride)

Toll-like Receptor (TLR),TLR7/8 agonist 1,TLR7/8 agonist 1 dihydrochloride,TLR-7/8 agonist 1 dihydrochloride,Inhibitor,inhibit

TLR7/8 agonist 1 2HCl

1620278-72-9