Secoisolariciresinol diglucoside

Product Name: Secoisolariciresinol diglucoside
CAS No.: 257930-74-8
Chemical Name: Secoisolariciresinol diglucoside
Synonyms: (S,S)-SDG;(S,S)-Secoisolariciresinol diglucoside;Secoisolariciresinoldiglucoside/(SS)-Secoisolariciresinoldiglucoside;β-D-Glucopyranoside, (2S,3S)-2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]-1,4-butanediyl bis-
CBNumber: CB03383971
Molecular Formula: C32H46O16
Formula Weight: 686.7
MOL File: 257930-74-8.mol

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Secoisolariciresinol diglucoside Property

Boiling point:: 989.2±65.0 °C(Predicted)
Density: 1.52±0.1 g/cm3(Predicted)
pka: 9.80±0.20(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-7895
Product name: Secoisolariciresinol diglucoside
Purity: 99.94%
Packaging: 5mg
Price: $96
Updated: 2021/12/16

ChemScene

Product number: CS-7895
Product name: Secoisolariciresinol diglucoside
Purity: 99.94%
Packaging: 10mg
Price: $168
Updated: 2021/12/16

ChemScene

Product number: CS-7895
Product name: Secoisolariciresinol diglucoside
Purity: 99.94%
Packaging: 25mg
Price: $336
Updated: 2021/12/16

ChemScene

Product number: CS-7895
Product name: Secoisolariciresinol diglucoside
Purity: 99.94%
Packaging: 50mg
Price: $468
Updated: 2021/12/16

ChemScene

Product number: CS-7895
Product name: Secoisolariciresinol diglucoside
Purity: 99.94%
Packaging: 100mg
Price: $804
Updated: 2021/12/16

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Secoisolariciresinol diglucoside Chemical Properties,Usage,Production

Uses

Secoisolariciresinol diglucoside ((S,S)-SDG), the main lignan in wholegrain flaxseed, is known for its beneficial effects including anti-inflammatory, antioxidant, anti-mutagenic, anti-microbial, anti-obesity, hypolipidemic, and neuroprotective effects[1][2].

Biological Activity

Secoisolariciresinol diglucoside ((S,S)-SDG), the major lignan in whole wheat flaxseed, has anti-inflammatory, antioxidant, anti-mutagenic, antimicrobial, anti-obesity, hypolipidemic and neuroprotective effects.

in vitro

Secoisolariciresinol diglucoside (1-500 μM) possesses strong reducing power and high free radical scavenging activity for hydroxyl, peroxyl and DPPH free radicals.

in vivo

Secoisolariciresinol diglucoside (4 mg/mouse; a single po) diminishes leukocyte adhesion and migration across blood-brain barrier (BBB) in neuroinflammation.

Animal Model: < /td>	Hand feeding mice (10 weeks old, male) are injected with TNFα
Dosage:	4 mg/mouse
Administration:	Po 2 h before ic administration of TNFα
Result:	Attenuated adhesion of leukocytes to the endothelium by 50% and attenuated migration of leukocytes across the BBB by 64%.

References

[1] Mishra OP, et al. Synthesis and antioxidant evaluation of (S,S)- and (R,R)-secoisolariciresinol diglucosides (SDGs). Bioorg Med Chem Lett. 2013 Oct 1;23(19):5325-8. DOI:10.1016/j.bmcl.2013.07.062
[2] Rom S, et, al. Secoisolariciresinol diglucoside is a blood-brain barrier protective and anti-inflammatory agent: implications for neuroinflammation. J Neuroinflammation. 2018 Jan 27;15(1):25. DOI:10.1186/s12974-018-1065-0

Secoisolariciresinol diglucoside Preparation Products And Raw materials

Raw materials

Preparation Products

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Secoisolariciresinol diglucoside Suppliers

China 22 United States 2 Global 24

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257930-74-8, Secoisolariciresinol diglucosideRelated Search:

β-D-Glucopyranoside, (2S,3S)-2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]-1,4-butanediyl bis-

Secoisolariciresinoldiglucoside/(SS)-Secoisolariciresinoldiglucoside

(S,S)-SDG

(S,S)-Secoisolariciresinol diglucoside

257930-74-8