BPV(PIC)

Product Name: BPV(PIC)
CAS No.: 148556-27-8
Chemical Name: BPV(PIC)
Synonyms: BPV(PIC);K2 [VO(O2)2C6H4NO2] 2 H2O;bpV(pic) (potassium hydrate);Dipotassium Bisperoxovanadium(pic) dihydrate;DIPOTASSIUM BISPEROXO(PICOLINATO)OXOVANADATE (V);Dipotassium bisperoxo (picolinato) oxovanadate (V) dihydrate
CBNumber: CB0345392
Molecular Formula: C6H8K2NO9V-3
Formula Weight: 367.26712
MOL File: 148556-27-8.mol

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BPV(PIC) Property

storage temp.: -20°C
solubility: H2O: soluble20mg/mL, clear
form: powder
color: faint yellow to dark yellow

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Safety

Hazard Codes: Xi
Risk Statements: 36/38
Safety Statements: 26
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0885
Product name: bpV(pic)
Purity: ≥95% V basis
Packaging: 5mg
Price: $104
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0885
Product name: bpV(pic)
Purity: ≥95% V basis
Packaging: 25mg
Price: $167.6
Updated: 2024/03/01

Cayman Chemical

Product number: 14434
Product name: bpV(pic) (potassium hydrate)
Purity: ≥96%
Packaging: 5mg
Price: $78
Updated: 2024/03/01

Cayman Chemical

Product number: 14434
Product name: bpV(pic) (potassium hydrate)
Purity: ≥96%
Packaging: 25mg
Price: $330
Updated: 2024/03/01

TRC

Product number: V785033
Product name: bpV(pic)
Packaging: 5mg
Price: $70
Updated: 2021/12/16

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BPV(PIC) Chemical Properties,Usage,Production

Uses

bpV(pic) is a bisperoxovanadium (bpV) compound that inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 = 31 nM). It also inhibits the vascular endothelial PTP, PTP-β (IC50 = 12.7 μM), and PTP-1βB (IC50 = 61 μM). bpV(pic) is also known to be an insulin mimetic capable of activating the insulin receptor kinase of cultured hepatoma cells, stimulating lipogenesis in adipocytes, and inhibiting the dephosphorylation of autophosphorylated insulin receptors and epidermal growth factor receptors of rat liver endosomes.

Uses

bpV(pic) is a potent protein PTP inhibitor.

Biochem/physiol Actions

bpV(pic) is a bisperoxovanadium inhibitor of protein phosphotyrosine phosphatases with selectivity for phosphatase and tensin homolog (PTEN), a tumour suppressor phosphatase involved in cell cycle regulation. IC50 values for bpV(pic) are 31 nM for PTEN compared to 12.7 μM for PTPβ and 61 μM for PTP-1β. bpV(pic) can also act as an insulin mimetic and activate insulin receptor kinase (IRK).

BPV(PIC) Preparation Products And Raw materials

Raw materials

Preparation Products

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BPV(PIC) Suppliers

China 42 Switzerland 1 United Kingdom 1 United States 5 Global 49

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148556-27-8, BPV(PIC)Related Search:

DIPOTASSIUM BISPEROXO(PICOLINATO)OXOVANADATE (V)

BPV(PIC)

Dipotassium bisperoxo (picolinato) oxovanadate (V) dihydrate

Dipotassium Bisperoxovanadium(pic) dihydrate

K2 [VO(O2)2C6H4NO2] 2 H2O

bpV(pic) (potassium hydrate)

148556-27-8