BOC-N-ME-TYR-OH

Product Name: BOC-N-ME-TYR-OH
CAS No.: 82038-34-4
Chemical Name: BOC-N-ME-TYR-OH
Synonyms: Boc-MeTyr-OH;BOC-N-ME-TYR-OH;Boc-N-Me-L-Tyr-OH;BOC-N-Methyl-L-tyrosine;BOC-N-ME-TYR-OH USP/EP/BP;N-Boc-N-methyl-L-tyrosine;N-tert-Butoxycarbonyl-N-methyl-L-tyrosine;N-[(1,1-DiMethylethoxy)carbonyl]-N-Methyl-L-tyrosine;L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl-;(S)-2-((tert-butoxycarbonyl)(Methyl)aMino)-3-(4-hydroxyphenyl)propanoic acid
CBNumber: CB0347725
Molecular Formula: C15H21NO5
Formula Weight: 295.33
MOL File: 82038-34-4.mol

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BOC-N-ME-TYR-OH Property

Melting point:: 140-142℃
Density: 1.220
storage temp.: 2-8°C
solubility: soluble in Ethyl Acetate, Methanol
form: Oil
color: Colourless
CAS DataBase Reference: 82038-34-4(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: M294435
Product name: N-Methyl-N-t-butoxycarbonyl-L-tyrosine
Packaging: 2.5g
Price: $1100
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0002010
Product name: N-METHYL-N-T-BUTOXYCARBONYL-L-TYROSINE
Purity: 95.00%
Packaging: 1G
Price: $1267
Updated: 2021/12/16

ChemScene

Product number: CS-0154824
Product name: Boc-MeTyr-OH
Packaging: 5g
Price: $511
Updated: 2021/12/16

Matrix Scientific

Product number: 132710
Product name: (S)-2-((tert-Butoxycarbonyl)(methyl)amino)-3-(4-hydroxyphenyl)propanoicacid
Purity: 97%
Packaging: 1g
Price: $1350
Updated: 2021/12/16

ChemScene

Product number: CS-0154824
Product name: Boc-MeTyr-OH
Packaging: 25g
Price: $1509
Updated: 2021/12/16

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BOC-N-ME-TYR-OH Chemical Properties,Usage,Production

Chemical Properties

Colourless Oil

Uses

BOC-N-ME-TYR-OH is used in the preparation of tyrosyl derivatives as P2X7 receptor modulators.

Synthesis

112196-58-4

82038-34-4

Methyl (S)-2-((tert-butoxycarbonyl)(methyl)amino)-3-(4-((tert-butyldimethylsilyl)oxy)phenyl)propionate (57) (4.0 g, 9.44 mmol) was used as a raw material, which was dissolved in a mixed solvent of THF:MeOH:H2O (3:1:1, 14.4 mL:4.8 mL:4.8 mL). LiOH-H2O (0.714 g, 17.02 mmol) was added to this solution at 0 °C. The reaction mixture was stirred at the same temperature for 1 h. LCMS monitoring showed complete consumption of the feedstock. After completion of the reaction, the reaction mixture was diluted with water (40 mL) and ethyl acetate (50 mL). The aqueous layer was acidified to pH 4-5 with 5% citric acid solution and subsequently extracted with ethyl acetate (2 x 100 mL). The organic layers were combined, dried over sodium sulfate, and concentrated under reduced pressure to afford (S)-2-((tert-butoxycarbonyl)(methyl)amino)-3-(4-hydroxyphenyl)propanoic acid (58) (2.78 g, 9.4 mmol, 100% yield) as a slightly reddish oil, which could be used for the next step of the reaction without further purification.MS (ESI): 294.2, [M-1]-.

References

[1] Tetrahedron Letters, 2018, p. 4267 - 4271
[2] Journal of Organic Chemistry, 1988, vol. 53, # 3, p. 487 - 499

BOC-N-ME-TYR-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-N-ME-TYR-OH Suppliers

Canada 1 China 56 Germany 2 India 2 United Kingdom 4 United States 13 Global 78

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Shanghai Chiral Chemicals Inc.

Tel: 021-37285021 13472570865
Fax: 86-021-51714507
Email: tym7xi@aliyun.com
Country: China
ProdList: 308
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5691
Advantage: 66

Lavem Chine Pharm Company

Tel: 028-62070218 18190869852
Fax: 86-28-8527-5264
Email: sales@lavemc.com
Country: China
ProdList: 214
Advantage: 67

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 12952
Advantage: 65

Shanghai Meishui Chemical Technology Co., Ltd

Tel: 021-60549325 18616193163
Fax: 021-33250306
Country: China
ProdList: 4526
Advantage: 56

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 42446
Advantage: 60

Sichuan Ampebiochem Co., Ltd.

Tel: 028-65294243 13981822079;18682730901
Email: sales@ampebiochem.com
Country: China
ProdList: 1000
Advantage: 58

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View Lastest Price from BOC-N-ME-TYR-OH manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: BOC-N-ME-TYR-OH 82038-34-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Career Henan Chemical Co

Product: BOC-N-ME-TYR-OH 82038-34-4
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2019-08-31

82038-34-4, BOC-N-ME-TYR-OHRelated Search:

Boc-N-Methyl-L-phenylglycine BOC-N-methyl-D-alanine Boc-N-methyl-L-phenylalanine Boc-N-alpha-methyl-O-benzyl-L-tyrosine N-tert-Butyloxycarbonyl-N-methyl-O-benzyl-L-threonine BOC-7-HYDROXY-TIC-OH BOC-3-I-TYR-OH BOC-N-ME-TYR-OH,BOC-N-ME-TYR-OH DCHA BOC-N-ME-TYR(AC)-OH DCHA BOC-METYR(ME)-OH DCHA O-TERT-BUTYLDIMETHYLSILYL-N-METHYL-N-T-BUTOXYCARBONYL-L-TYROSINE, METHYL ESTER BOC-N-ME-TYR-OH BOC-[15N]TYR-OH BOC-3-AMINO-TYR-OH BOC-N-ME-TYR(2,6-DICHLORO-BZL)-OH BOC-3-NITRO-TYR-OH,BOC-M-NITRO-TYR-OH BOC-L-M-TYR-OH, BOC-D-O-TYR-OH,

BOC-N-ME-TYR-OH

BOC-N-Methyl-L-tyrosine

N-tert-Butoxycarbonyl-N-methyl-L-tyrosine

(S)-2-((tert-butoxycarbonyl)(Methyl)aMino)-3-(4-hydroxyphenyl)propanoic acid

Boc-N-Me-L-Tyr-OH

N-Boc-N-methyl-L-tyrosine

Boc-MeTyr-OH

N-[(1,1-DiMethylethoxy)carbonyl]-N-Methyl-L-tyrosine

L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl-

BOC-N-ME-TYR-OH USP/EP/BP

82038-34-4

Amino Acids & Derivatives

Aromatics

Chiral Reagents

Tyrosine [Tyr, Y]