Lithium triisobutylhydroborate
Description Features Preparation- Product Name
- Lithium triisobutylhydroborate
- CAS No.
- 38721-52-7
- Chemical Name
- Lithium triisobutylhydroborate
- Synonyms
- L-selectride;LITHIUM TRI-SEC-BUTYLBOROHYDRIDE;lithium tri-sec-butylborohydride solution;Lithium tri-sec-butylhydridoborate, 1.0M solution in THF, packaged under Argon in resealable ChemSealTM bottles;1.0MinTHF;L-SELECTRIDE(R);Lithium tri-sec;1.0MsolutioninTHF;ithium tri-sec-butyL;l-selectride solution
- CBNumber
- CB0349017
- Molecular Formula
- C12H28B.Li
- Formula Weight
- 190.1
- MOL File
- 38721-52-7.mol
Lithium triisobutylhydroborate Property
- Density
- 0.89 g/mL at 25 °C
- Flash point:
- 1 °F
- storage temp.
- Flammables area
- solubility
- Miscible with tetrahydrofuran.
- form
- Liquid
- color
- Colorless to yellow
- Water Solubility
- reacts
- Sensitive
- Moisture Sensitive
- BRN
- 4007327
- InChIKey
- ACJKNTZKEFMEAK-UHFFFAOYSA-N
- CAS DataBase Reference
- 38721-52-7(CAS DataBase Reference)
- EPA Substance Registry System
- Borate(1-), hydrotris(1-methylpropyl)-, lithium, (T-4)- (38721-52-7)
Safety
- Hazard Codes
- F,C
- Risk Statements
- 11-14/15-17-34-35-19-40-37
- Safety Statements
- 16-26-36/37/39-43-45-7/8-30
- RIDADR
- UN 3394 4.2/PG 1
- WGK Germany
- 1
- F
- 10
- TSCA
- Yes
- HazardClass
- 4.3
- PackingGroup
- II
- HS Code
- 29319090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H250Catches fire spontaneously if exposed to air
H260In contact with water releases flammable gases which may ignite spontaneously
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
H335May cause respiratory irritation
H351Suspected of causing cancer
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P231+P232Handle under inert gas. Protect from moisture.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P370+P378In case of fire: Use … for extinction.
P402+P404Store in a dry place. Store in a closed container.
P422Store contents under …
N-Bromosuccinimide Price
- Product number
- 178497
- Product name
- L-Selectride? solution
- Purity
- 1.0M in THF
- Packaging
- 8l
- Price
- $2090
- Updated
- 2024/03/01
- Product number
- 043034
- Product name
- Lithium tri-sec-butylborohydride, 1.0M solution in THF, packaged under Argon in resealable ChemSeal? bottles
- Packaging
- 100ml
- Price
- $82
- Updated
- 2024/03/01
- Product number
- 043034
- Product name
- Lithium tri-sec-butylborohydride, 1.0M solution in THF, packaged under Argon in resealable ChemSeal? bottles
- Packaging
- 500ml
- Price
- $332
- Updated
- 2024/03/01
- Product number
- 03-1400
- Product name
- Lithium triisobutylhydroborate
- Packaging
- 100g
- Price
- $77
- Updated
- 2024/03/01
- Product number
- 03-1400
- Product name
- Lithium triisobutylhydroborate
- Packaging
- 500g
- Price
- $308
- Updated
- 2024/03/01
Lithium triisobutylhydroborate Chemical Properties,Usage,Production
Description
Lithium tri-sec-butylborohydride, commercially available as a one molar solution in tetrahydrofuran. It is widely used as a mild and strong reducing agent with high stereoselectivity in organic synthesis.
Features
Lithium tri-sec-butylborohydride is a new type of hydride reducing agent, which has the characteristics of strong reducing ability and high regio- and stereoselectivity.
Preparation
Lithium triisobutylhydroborate can be prepared by:In a 3000ml three-necked flask, add 1000ml of 1mol/L tri-sec-butylboron tetrahydrofuran solution, add 1000ml of 1mol/L triethylenediamine tetrahydrofuran solution simultaneously, introduce nitrogen to start stirring, put the mixture of the two in an ice-water bath After cooling to 0° C., 1000 ml of a 1 mol/L lithium aluminum hydride solution in tetrahydrofuran was slowly added dropwise to the above mixed solution with a constant pressure funnel for about 10 hours.
Physical properties
clear colourless solution
Uses
Lithium triisobutylhydroborate is used as a reducing agent. Reagent for: Enantioselective synthesis of a-amino acids via reduction of N-tert-butanesulfinyl ketimine esters. Diastereoselective reduction reactions. Hydride reduction of the Danishefsky pyranones. Asymmetric reductive aldol reaction of enones with a-alkoxy aldehydes. Synthesis of alkanols by carbonylation reactions.
Uses
L-Selectride Solution is a reducing agent which is used in the preparation of oxygen heterocycles. Used also as a reactant in the synthesis of novel bicicyclo[3.1.0]hexane analags which may prove useful in the treatment of depression.
Lithium triisobutylhydroborate Preparation Products And Raw materials
Raw materials
Preparation Products
Lithium triisobutylhydroborate Suppliers
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- Japan
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View Lastest Price from Lithium triisobutylhydroborate manufacturers
- Product
- Lithium triisobutylhydroborate 38721-52-7
- Price
- US $9.90/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-14
- Product
- Lithium tri-sec-butylborohydride 38721-52-7
- Price
- US $0.00-0.00/kg
- Min. Order
- 100kg
- Purity
- 1±0.02M in THF
- Supply Ability
- 100 tons
- Release date
- 2022-11-07
- Product
- Lithium triisobutylhydroborate 38721-52-7
- Price
- US $120.00/g
- Min. Order
- 1g
- Purity
- 1M solution in THF
- Supply Ability
- 25kg
- Release date
- 2023-12-29