RO-31-8425

Product Name: RO-31-8425
CAS No.: 131848-97-0
Chemical Name: RO-31-8425
Synonyms: Ro 31-8245;RO-31-8425;RSYYBisindolylmaleimideXhydrochloride;Ro-31-8425 - CAS 131848-97-0 - Calbiochem;BisindolylMaleiMide X . hydrochloride [Ro 31-8425];3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 3-[8-(aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-
CBNumber: CB0353038
Molecular Formula: C26H24N4O2
Formula Weight: 424.49
MOL File: 131848-97-0.mol

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RO-31-8425 Property

Boiling point:: 736.1±60.0 °C(Predicted)
Density: 1.43±0.1 g/cm3(Predicted)
storage temp.: 0-6°C
solubility: DMSO: 10mg/mL
form: Red to orange-red solid
pka: 7.91±0.60(Predicted)
color: red to orange-red
InChI: 1S/C26H24N4O2/c1-29-14-18(16-6-2-4-8-19(16)29)23-24(26(32)28-25(23)31)22-17-7-3-5-9-20(17)30-11-10-15(13-27)12-21(22)30/h2-9,14-15H,10-13,27H2,1H3,(H,28,31,32)
InChIKey: QQKKPWJFHBFCTH-UHFFFAOYSA-N
SMILES: [n]21c3c(c(c2CC(CC1)CN)C4=C(C(=O)NC4=O)c5c6c([n](c5)C)cccc6)cccc3

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Safety

WGK Germany: WGK 1
HS Code: 2925199590
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 557514
Product name: Ro-31-8425
Packaging: 1mg
Price: $175
Updated: 2026/03/19

Iris Biotech GmbH

Product number: LS-4080
Product name: BisindolylmaleimideX
Packaging: 1mg
Price: $270
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0009782
Product name: BISINDOLYLMALEIMIDE X
Purity: 95.00%
Packaging: 5MG
Price: $516
Updated: 2021/12/16

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RO-31-8425 Chemical Properties,Usage,Production

Uses

Bisindolylmaleimide X is a selective inhibitor of PKC, also inhibits Cdk2 and GSK-3β.

Biological Activity

Cell permeable: yes', 'Primary Target
PKC', 'Product competes with ATP.', 'Reversible: yes', 'Target IC50: 15 nM for r at brain PKC; 8 nM for PKCα, 8 nM for PKCβI, 14 nM for PKCβII, 13 nM for PKCγ, and 39 nM for PKCε

RO-31-8425 Preparation Products And Raw materials

Raw materials

Preparation Products

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RO-31-8425 Suppliers

China 10 Japan 2 Switzerland 1 United Kingdom 1 United States 4 Global 18

TOSUN PHARM

Tel: 61855200 13326451905
Email: 3003386889@qq.com
Country: China
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Jinan Ruisi Pharmaceutical Technology Co., LTD

Tel: 0531-0531-69900633 19963472814
Email: changyuan20@163.com
Country: China
ProdList: 4869
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Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
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Adipogen Life Sciences

Tel: 41-6192660-40
Email: info@adipogen.com
Country: China
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Merck Millipore

Tel: 1-400-889-1988 400-889-1988
Email: bioscience@merckgroup.com
Country: China
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Merck KGaA

Tel: 21-20338288
Email: ordercn@merckgroup.com
Country: China
ProdList: 6038
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Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 52923
Advantage: 58

131848-97-0, RO-31-8425Related Search:

RO-31-8425,RO 31-8425 HYDROCHLORIDE,RO 31 8425 HCL RO-32-0432 RO-31-8425

RO-31-8425

BisindolylMaleiMide X . hydrochloride [Ro 31-8425]

3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione

Ro 31-8245

Ro-31-8425 - CAS 131848-97-0 - Calbiochem

RSYYBisindolylmaleimideXhydrochloride

1H-Pyrrole-2,5-dione, 3-[8-(aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-

131848-97-0

C26H24N4O2

C26H24N4O2HCl

inhibitor