Mechanisms of Resistance
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CHLORAMPHENICOL ACETYLTRANSFERASE

Mechanisms of Resistance
Product Name
CHLORAMPHENICOL ACETYLTRANSFERASE
CAS No.
9040-07-7
Chemical Name
CHLORAMPHENICOL ACETYLTRANSFERASE
Synonyms
EC 2.3.1.28;Chloramphenicol acetylase;Chloramphenicol transacetylase;CHLORAMPHENICOL ACETYLTRANFERASE;CHLORAMPHENICOL ACETYLTRANSFERASE;chloramphenicol acetyltransferase*from escherichi;ACETYL-COA: CHLORAMPHENICOL 3-O-ACETYLTRANSFERASE;CHLORAMPHENICOL ACETYLTRANSFERASEFROM ES CHERICHIA;CHLORAMPHENICOL ACETYLTRANSFERASEGLYCERO L SOLUTION;chloramphenicol acetyltransferase from escherichia coli
CBNumber
CB0360414
Molecular Formula
C11H12Cl2N2O5
Formula Weight
323.12938
MOL File
9040-07-7.mol
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CHLORAMPHENICOL ACETYLTRANSFERASE Property

storage temp. 
−20°C
form 
lyophilized powder
CAS DataBase Reference
9040-07-7
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
HCH0013979
Product name
CHLORAMPHENICOL ACETYLTRANSFERASE
Purity
95.00%
Packaging
5MG
Price
$499.41
Updated
2021/12/16
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CHLORAMPHENICOL ACETYLTRANSFERASE Chemical Properties,Usage,Production

Mechanisms of Resistance

The major mechanism of resistance to chloramphenicol is the production of a chloramphenicol acetyltransferase which converts the drug to either the monoacetate or the diacetate. These derivatives are unable to bind to the bacterial 50S ribosomal subunit and thus cannot inhibit peptidyl transferase activity. The chloramphenicol acetyltransferase (CAT) gene is usually encoded on a plasmid or transposon and may transpose to the chromosome. Surprisingly, in view of the very limited use of chloramphenicol, resistance is not uncommon, even in Esch. coli, although it is most frequently seen in organisms that are multiresistant.

CHLORAMPHENICOL ACETYLTRANSFERASE Preparation Products And Raw materials

Raw materials

Preparation Products

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CHLORAMPHENICOL ACETYLTRANSFERASE Suppliers

Riedel-de Haen AG
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Promega Corporation
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techserv@promega.com
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Creative Enzymes
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Creative Enzymes
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contact@creative-enzymes.com
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9040-07-7, CHLORAMPHENICOL ACETYLTRANSFERASERelated Search:


  • CHLORAMPHENICOL ACETYLTRANFERASE
  • CHLORAMPHENICOL ACETYLTRANSFERASE
  • EC 2.3.1.28
  • ACETYL-COA: CHLORAMPHENICOL 3-O-ACETYLTRANSFERASE
  • chloramphenicol acetyltransferase*from escherichi
  • CHLORAMPHENICOL ACETYLTRANSFERASEFROM ES CHERICHIA
  • CHLORAMPHENICOL ACETYLTRANSFERASEGLYCERO L SOLUTION
  • chloramphenicol acetyltransferase from escherichia coli
  • Acetyl-CoA: chloramphenicol 3-O-acetyltransferase, CAT
  • Chloramphenicol transacetylase
  • Chloramphenicol acetylase
  • Chloramphenicol Acetyltransferase from Escherichia coli lyophilized powder, 50,000-150,000 units/mg protein (Lowry)
  • 9040-07-7
  • Diagnostic and Analytical Enzymes
  • Enzymes, Inhibitors, and Substrates
  • Biochemicals and Reagents
  • Application Index
  • BioChemical
  • Proteomics
  • Proteomics and Protein Expression
  • Reporter Gene Analysis and Detection
  • Recombinant Protein Expression and Analysis