ChemicalBook > CAS DataBase List > 2-Chloro-6-methylaniline
2-Chloro-6-methylaniline
- Product Name
- 2-Chloro-6-methylaniline
- CAS No.
- 87-63-8
- Chemical Name
- 2-Chloro-6-methylaniline
- Synonyms
- 6-CHLORO-O-TOLUIDINE;6-CHLORO-2-METHYLANILINE;6COT;NSC 60121;oro-6-methyL;TIMTEC-BB SBB004153;6-chloro-o-toluidin;2-Chloro-6-methylani;6-CHLORO-2-TOLUIDINE;6-ChIoro-o-toluidine
- CBNumber
- CB0361613
- Molecular Formula
- C7H8ClN
- Formula Weight
- 141.6
- MOL File
- 87-63-8.mol
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2-Chloro-6-methylaniline Property
- Melting point:
- 10-12 °C(lit.)
- Boiling point:
- 215 °C(lit.)
- Density
- 1.152 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.576(lit.)
- Flash point:
- 210 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- pka
- 2.51±0.10(Predicted)
- form
- Oil
- color
- Clear Colourless to Pale Purple
- Water Solubility
- Immiscible
- BRN
- 774624
- InChIKey
- WFNLHDJJZSJARK-UHFFFAOYSA-N
- CAS DataBase Reference
- 87-63-8(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzenamine, 2-chloro-6-methyl-(87-63-8)
- EPA Substance Registry System
- 6-Chloro-2-methylaniline (87-63-8)
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Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-36-36/37/39
- RIDADR
- UN 3429 6.1/PG 3
- WGK Germany
- 3
- RTECS
- XU5100000
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29214300
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H341Suspected of causing genetic defects
H373May cause damage to organs through prolonged or repeated exposure
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P201Obtain special instructions before use.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- C51008
- Product name
- 2-Chloro-6-methylaniline
- Purity
- 98%
- Packaging
- 1g
- Price
- $35.4
- Updated
- 2023/01/07
TCI Chemical
- Product number
- A1959
- Product name
- 2-Chloro-6-methylaniline
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $70
- Updated
- 2024/03/01
TCI Chemical
- Product number
- A1959
- Product name
- 2-Chloro-6-methylaniline
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $205
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- L02629
- Product name
- 2-Chloro-6-methylaniline, 98%
- Packaging
- 25g
- Price
- $315.65
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- L02629
- Product name
- 2-Chloro-6-methylaniline, 98%
- Packaging
- 1g
- Price
- $37.1
- Updated
- 2021/12/16
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2-Chloro-6-methylaniline Chemical Properties,Usage,Production
Description
2-chloro-6-methylaniline is an important organic synthesis intermediate widely applied to chemical pharmacy, pesticides, and organic synthesis. In the aspects of chemical pharmacy and pesticides, 2-chloro-6-methylaniline can be used as a reaction starting material to participate in the preparation processes of tyrosine kinase inhibitors dasatinib, indazole derivatives with anti-breast cancer activity, 2-methyl-6-chlorophenyl sulfonylurea derivatives with bacteriostatic activity and the like; in the aspect of organic synthesis, 2-chloro-6-methylaniline can introduce chemical groups such as hydrazine, nitro, cyano, halogen (F, Cl, Br), and the like into an aromatic ring through diazotization reaction, thereby participating in wide chemical reactions.
Chemical Properties
clear yellow to red-brown liquid
Chemical Properties
The chloromethylanilines are colorless or white crystalline solids or liquids, some have a mild fishy odor.
Uses
2-Chloro-6-methylaniline is a substituted aniline used in the preparation of various pharmaceutical compounds. 2-Chloro-6-methylaniline showed inhibition of the polymerization of vinyl acetate.
Preparation
A preparation method of 2-chloro-6-methylaniline takes 3-chloro-5-methyl-4-nitroaniline as a starting material, water as a solvent, and sulfuric acid as a reactant. Eliminates amino groups through diazotization reaction, reduces by hypophosphorous acid to obtain an intermediate, and finally takes iron powder as reducing nitro groups to prepare the 2-chloro-6-methylaniline through a one-pot reaction.
Potential Exposure
Most of the isomers are used in dyestuff manufacture. The 3-chloro-para isomer is used to kill birds. It is marketed as pelleted bait for control of bird populations.
Shipping
UN2239 Chlorotoluidines, solid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN3429 Chlorotoluidines, liquid, Hazard Class: 6.1; Labels: 6.1- Poisonous materials
Incompatibilities
Incompatible with oxidizers, strong acids; chloroformates, and acid anhydrides, isocyanates, aldehydes forming fire and explosive hazards.
2-Chloro-6-methylaniline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Chloro-6-methylaniline manufacturers
Henan Fengda Chemical Co., Ltd
- Product
- 2-Chloro-6-methylaniline 87-63-8
- Price
- US $50.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99
- Supply Ability
- g-kg-tons,free sample is available
- Release date
- 2024-01-02
Hebei Duling International Trade Co. LTD
- Product
- 2-Chloro-6-methylaniline, 98% 87-63-8
- Price
- US $42.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 5000 tons
- Release date
- 2023-02-15
Henan Aochuang Chemical Co.,Ltd.
- Product
- 2-Chloro-6-methylaniline 87-63-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-09-30
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