METHYL 4-BROMO-2,5-DIMETHYL-1H-PYRROLE-3-CARBOXYLATE

Product Name: METHYL 4-BROMO-2,5-DIMETHYL-1H-PYRROLE-3-CARBOXYLATE
CAS No.: 120935-94-6
Chemical Name: METHYL 4-BROMO-2,5-DIMETHYL-1H-PYRROLE-3-CARBOXYLATE
Synonyms: METHYL 4-BROMO-2,5-DIMETHYL-1H-PYRROLE-3-CARBOXYLATE;4-Bromo-2,5-dimethyl-1H-pyrrole-3-carboxylic acid methyl ester;1H-Pyrrole-3-carboxylic acid, 4-bromo-2,5-dimethyl-, methyl ester
CBNumber: CB0379243
Molecular Formula: C8H10BrNO2
Formula Weight: 232.07
MOL File: 120935-94-6.mol

More

Less

METHYL 4-BROMO-2,5-DIMETHYL-1H-PYRROLE-3-CARBOXYLATE Property

Boiling point:: 344.5±37.0 °C(Predicted)
Density: 1.503±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 15.20±0.50(Predicted)

More

Less

Safety

Hazard Codes: Xi
Hazard Note: Irritant

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

AK Scientific

Product number: 3564AL
Product name: Methyl4-bromo-2,5-dimethyl-1H-pyrrole-3-carboxylate
Packaging: 100mg
Price: $227
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0026455
Product name: METHYL 4-BROMO-2,5-DIMETHYL-1H-PYRROLE-3-CARBOXYLATE
Purity: 95.00%
Packaging: 1G
Price: $720.23
Updated: 2021/12/16

AK Scientific

Product number: 3564AL
Product name: Methyl4-bromo-2,5-dimethyl-1H-pyrrole-3-carboxylate
Packaging: 1g
Price: $756
Updated: 2021/12/16

Matrix Scientific

Product number: 126961
Product name: Methyl4-bromo-2,5-dimethyl-1H-pyrrole-3-carboxylate
Purity: >95%
Packaging: 1g
Price: $1044
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0026455
Product name: METHYL 4-BROMO-2,5-DIMETHYL-1H-PYRROLE-3-CARBOXYLATE
Purity: 95.00%
Packaging: 10G
Price: $1619.55
Updated: 2021/12/16

More

Less

METHYL 4-BROMO-2,5-DIMETHYL-1H-PYRROLE-3-CARBOXYLATE Chemical Properties,Usage,Production

Synthesis

69687-80-5

120935-94-6

Methyl 2,5-dimethyl-1H-pyrrole-3-carboxylate (6.85 g, 45.0 mmol) was used as a raw material and was mixed with triethylamine (8.7 mL, 63.0 mmol) and dichloromethane (270 mL). Pyridinium bromide (15.7 g, 15.7 mmol) was added to the mixture in batches at 0 °C. The reaction mixture was stirred at 0 °C for 2 h before being poured into brine and extracted with ethyl acetate. The organic layers were combined, dried with anhydrous magnesium sulfate and subsequently concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: hexane-ethyl acetate). The final product, methyl 4-bromo-2,5-dimethyl-1H-pyrrole-3-carboxylate, was recrystallized by hexane-ethyl acetate to give yellow crystals (7.59 g, 92% yield).1H NMR (300 MHz, CDCl3) δ: 2.19 (3H, s), 2.47 (3H, s), 3.82 (3H, s), 8.20 (1H, s).

References

[1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 1, p. 422 - 434
[2] Journal of Medicinal Chemistry, 1993, vol. 36, # 19, p. 2739 - 2744
[3] Patent: EP1466902, 2004, A1. Location in patent: Page 31

METHYL 4-BROMO-2,5-DIMETHYL-1H-PYRROLE-3-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

METHYL 4-BROMO-2,5-DIMETHYL-1H-PYRROLE-3-CARBOXYLATE Suppliers

China 11 Germany 1 India 1 United Kingdom 1 United States 8 Global 22

Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9793
Advantage: 50

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Aikon International Limited

Tel: 025-66113011 13155353615
Fax: (7)02557626880
Email: qzhang@aikonchem.com
Country: China
ProdList: 15394
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418684 +8618949823763
Fax: 0086-551-65418684
Email: sales@tnjchem.com
Country: China
ProdList: 25356
Advantage: 58

Changzhou Kechem Bio-Scientific Co., LTD.

Tel: 0519-68985668 13685222090
Fax: qq735434464
Email: sales@kechem.cn
Country: China
ProdList: 26028
Advantage: 58

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 52923
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: +undefined18143011203
Email: info@chemextension.com
Country: China
ProdList: 42056
Advantage: 58

120935-94-6, METHYL 4-BROMO-2,5-DIMETHYL-1H-PYRROLE-3-CARBOXYLATERelated Search:

ACETONE-D6 2,5-DIMETHYLPYRROLE-3-CARBOXYLIC ACID METHYL 4-BROMO-2,5-DIMETHYL-1H-PYRROLE-3-CARBOXYLATE 3-BROMO-1H-PYRROLE

METHYL 4-BROMO-2,5-DIMETHYL-1H-PYRROLE-3-CARBOXYLATE

4-Bromo-2,5-dimethyl-1H-pyrrole-3-carboxylic acid methyl ester

1H-Pyrrole-3-carboxylic acid, 4-bromo-2,5-dimethyl-, methyl ester

120935-94-6

C8H10BrNO2