2-AMINO-2-(3-(TRIFLUOROMETHYL)PHENYL)ACETIC ACID HYDROCHLORIDE
- Product Name
- 2-AMINO-2-(3-(TRIFLUOROMETHYL)PHENYL)ACETIC ACID HYDROCHLORIDE
- CAS No.
- 1134915-25-5
- Chemical Name
- 2-AMINO-2-(3-(TRIFLUOROMETHYL)PHENYL)ACETIC ACID HYDROCHLORIDE
- Synonyms
- 2-(3-Trifluoromethylphenyl)glycine (hydrochloride);AMINO[3-(TRIFLUOROMETHYL)PHENYL]ACETIC ACID HYDROCHLORIDE;2-amino-2-[3-(trifluoromethyl)phenyl]acetic acid,hydrochlor;2-AMINO-2-(3-(TRIFLUOROMETHYL)PHENYL)ACETIC ACID HYDROCHLORIDE;rel-(2R)-2-amino-2-[3-(trifluoromethyl)phenyl]acetic acid hydrochloride
- CBNumber
- CB0380829
- Molecular Formula
- C9H9ClF3NO2
- Formula Weight
- 255.62
- MOL File
- Mol file
2-AMINO-2-(3-(TRIFLUOROMETHYL)PHENYL)ACETIC ACID HYDROCHLORIDE Property
- storage temp.
- Sealed in dry,Room Temperature
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- AS24641
- Product name
- 2-Amino-2-[3-(trifluoromethyl)phenyl]acetic Acid Hydrochloride
- Purity
- 97+%
- Packaging
- 1g
- Price
- $155
- Updated
- 2021/12/16
- Product number
- 5428AJ
- Product name
- 2-Amino-2-[3-(trifluoromethyl)phenyl]aceticacidhydrochloride
- Packaging
- 1g
- Price
- $197
- Updated
- 2021/12/16
- Product number
- AS24641
- Product name
- 2-Amino-2-[3-(trifluoromethyl)phenyl]acetic Acid Hydrochloride
- Purity
- 97+%
- Packaging
- 5G
- Price
- $461
- Updated
- 2021/12/16
- Product number
- HCH0098000
- Product name
- 2-AMINO-2-(3-(TRIFLUOROMETHYL)PHENYL)ACETIC ACID HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1431.05
- Updated
- 2021/12/16
- Product number
- A184338
- Product name
- 2-Amino-2-(3-(trifluoromethyl)phenyl)aceticacidhydrochloride
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $24
- Updated
- 2021/12/16
2-AMINO-2-(3-(TRIFLUOROMETHYL)PHENYL)ACETIC ACID HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
2-(3-Trifluoromethylphenyl)glycine hydrochloride is a precursor of substituted 2-acetamido-5-aryl-l, 2,4-triazolones. Substituted 2-acetamido-5-aryl-l, 2,4-triazolones are dual V1a/V2 receptor antagonists and can be used in cardiovascular disease research[1].
Synthesis
146621-92-3
1134915-25-5
Example 95A: Synthesis of 2-amino-2-(3-trifluoromethylphenyl)acetic acid hydrochloride 1.00 g (3.13 mmol) of N-tert-butoxycarbonyl-2-(3-trifluoromethylphenyl)-DL-glycine was mixed with 15.7 mL of a dioxane solution of 4N HCl and stirred overnight at room temperature. Upon completion of the reaction, the volatile components were removed using a rotary evaporator. The residue was dried under high vacuum (HV) to give 795 mg (99% of theoretical yield) of 2-amino-2-(3-trifluoromethylphenyl)acetic acid hydrochloride.LC/MS [Method 2]: rt = 0.79 min; m/z = 220 (M + H)+.
References
[1] Ulf Brüggemeier, et al. Substituted 2-acetamido-5-aryl-1,2,4-triazolones and use thereof. WO2010105770A1
2-AMINO-2-(3-(TRIFLUOROMETHYL)PHENYL)ACETIC ACID HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
2-AMINO-2-(3-(TRIFLUOROMETHYL)PHENYL)ACETIC ACID HYDROCHLORIDE Suppliers
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- Country
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