1-(5-BROMOPYRIMIDIN-2-YL)-4-PIPERIDINOL

Product Name: 1-(5-BROMOPYRIMIDIN-2-YL)-4-PIPERIDINOL
CAS No.: 887425-47-0
Chemical Name: 1-(5-BROMOPYRIMIDIN-2-YL)-4-PIPERIDINOL
Synonyms: 1-(5-bromo-2-pyrimidinyl)-4-piperidinol;1-(5-BROMOPYRIMIDIN-2-YL)PIPERIDIN-4-OL;1-(5-BROMOPYRIMIDIN-2-YL)-4-PIPERIDINOL;4-Piperidinol, 1-(5-bromo-2-pyrimidinyl)-;5-Bromo-2-(4-hydroxypiperidino)pyrimidine
CBNumber: CB0388274
Molecular Formula: C9H12BrN3O
Formula Weight: 258.12
MOL File: 887425-47-0.mol

More

Less

1-(5-BROMOPYRIMIDIN-2-YL)-4-PIPERIDINOL Property

storage temp.: Sealed in dry,Room Temperature
Appearance: White to off-white Solid

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: B786505
Product name: 1-(5-Bromopyrimidin-2-yl)piperidin-4-ol
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB153928
Product name: 1-(5-Bromopyrimidin-2-yl)-4-piperidinol
Packaging: 1g
Price: $87
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB153928
Product name: 1-(5-Bromopyrimidin-2-yl)-4-piperidinol
Packaging: 2g
Price: $151
Updated: 2021/12/16

Matrix Scientific

Product number: 072018
Product name: 1-(5-Bromopyrimidin-2-yl)-4-piperidinol
Purity: 95+%
Packaging: 1g
Price: $185
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: COR0001157
Product name: 1-(5-BROMOPYRIMIDIN-2-YL)-4-PIPERIDINOL
Purity: 95.00%
Packaging: 1G
Price: $203.7
Updated: 2021/12/16

More

Less

1-(5-BROMOPYRIMIDIN-2-YL)-4-PIPERIDINOL Chemical Properties,Usage,Production

Synthesis

5382-16-1

32779-36-5

887425-47-0

Step 1: 4-hydroxypiperidine (1.93 g, 10 mmol), diisopropylethylamine (5.22 mL, 30 mmol), 5-bromo-2-chloropyrimidine (1.01 g, 10 mmol), and acetonitrile (50 mL) were added to a round-bottomed flask under nitrogen protection. The reaction mixture was heated to reflux for 15 hours and then concentrated under reduced pressure to remove the solvent. The crude product was dissolved in dichloromethane (150 mL), washed sequentially with water (2 x 20 mL), saturated saline (1 x 20 mL), dried over anhydrous sodium sulfate and filtered. The filtrate was concentrated under reduced pressure and purified by silica gel column chromatography to afford 1-(5-bromo-2-pyrimidinyl)-4-hydroxypiperidine (16) (2.55 g, 99% yield) as a white solid.1H NMR (400 MHz, DMSO-d6) δ: 8.34 (s, 2H), 4.73 (d, J = 4.0 Hz, 1H), 4.17-4.12 (m 2H), 3.74-3.68 (m, 1H), 3.28-3.22 (m, 2H), 1.76-1.70 (m, 2H), 1.33-1.25 (m, 2H); LCMS (ESI): m/z 260 [M+H]+.

References

[1] Patent: WO2008/8895, 2008, A1. Location in patent: Page/Page column 70
[2] Patent: CN106167486, 2016, A. Location in patent: Paragraph 0388; 0389-0391
[3] Patent: WO2008/46226, 2008, A1. Location in patent: Page/Page column 58
[4] Patent: US2008/182838, 2008, A1. Location in patent: Page/Page column 20

1-(5-BROMOPYRIMIDIN-2-YL)-4-PIPERIDINOL Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1-(5-BROMOPYRIMIDIN-2-YL)-4-PIPERIDINOL Suppliers

China 23 Germany 1 India 1 United Kingdom 3 United States 7 Global 35

NovoChemy Ltd.

Tel: 021-31261262/ 49 (0)17662837245
Fax: (0)21-33250524
Email: sales@novochemy.com
Country: Germany
ProdList: 6328
Advantage: 58

Shanghai Jovan Biochemical Technology Co. Ltd.

Tel: +86-021-61654350
Fax: +86-021-61654350
Email: 1245958370@qq.com
Country: China
ProdList: 2982
Advantage: 50

ShangHai Angti Biotechnology Co., Ltd.

Tel: 13764913901
Fax: -
Email: info@angtibio.com
Country: China
ProdList: 4985
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Yantai ShengKailun Chemical Technology Co., Ltd.

Tel: 13356901049
Fax: QQ：1025383091
Email: 3119594100@qq.com
Country: China
ProdList: 7964
Advantage: 55

Combiphos (Shanghai) Biological Technology Co., Ltd.

Tel: 021-65232103 17602124823
Email: combiphos@vip.qq.com
Country: China
ProdList: 30000
Advantage: 58

Aikon International Limited

Tel: 025-66061636 18013972705
Fax: (3)02557626880
Email: qqyang@aikonchem.com
Country: China
ProdList: 15814
Advantage: 58

Nanjing SynTitan Pharmaceutical Co., Ltd.

Tel: 025-57027686 17372956142
Fax: 025-57027686
Email: li_lan@syntitan.com
Country: China
ProdList: 9998
Advantage: 58

Nanjing Asfam Pharmaceutical Technology Co., Ltd.

Tel: 025-58867862 18751812725
Fax: 02558867862
Email: sales@ace-pharm.com
Country: China
ProdList: 1985
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

More

Less

View Lastest Price from 1-(5-BROMOPYRIMIDIN-2-YL)-4-PIPERIDINOL manufacturers

Career Henan Chemical Co

Product: 1-(5-BROMOPYRIMIDIN-2-YL)-4-PIPERIDINOL 887425-47-0
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-13

887425-47-0, 1-(5-BROMOPYRIMIDIN-2-YL)-4-PIPERIDINOLRelated Search:

(5-BROMO-PYRIMIDIN-2-YL)-DIETHYL-AMINE 5-BROMO-2-(DIMETHYLAMINO)PYRIMIDINE 5-Bromo-2-(piperidin-1-yl)pyrimidine 5-BROMO-N-BUTYL-2-PYRIMIDINAMINE 8-(5-BROMO-PYRIMIDIN-2-YL)-1,4-DIOXA-8-AZA-SPIRO[4.5]DECANE 1-(5-BROMOPYRIMIDIN-2-YL)-4-PIPERIDINOL

1-(5-BROMOPYRIMIDIN-2-YL)-4-PIPERIDINOL

1-(5-BROMOPYRIMIDIN-2-YL)PIPERIDIN-4-OL

1-(5-bromo-2-pyrimidinyl)-4-piperidinol

5-Bromo-2-(4-hydroxypiperidino)pyrimidine

4-Piperidinol, 1-(5-bromo-2-pyrimidinyl)-

887425-47-0