N-(3,4-dichlorophenyl)-N-methylpropionamide

Product Name: N-(3,4-dichlorophenyl)-N-methylpropionamide
CAS No.: 15533-81-0
Chemical Name: N-(3,4-dichlorophenyl)-N-methylpropionamide
Synonyms: ELP-004;N-(3,4-dichlorophenyl)-N-methylpropanamide;N-(3,4-dichlorophenyl)-N-methylpropionamide;Propanamide, N-(3,4-dichlorophenyl)-N-methyl-
CBNumber: CB03956775
Molecular Formula: C10H11Cl2NO
Formula Weight: 232.11
MOL File: 15533-81-0.mol

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N-(3,4-dichlorophenyl)-N-methylpropionamide Property

Boiling point:: 336.8±32.0 °C(Predicted)
Density: 1.279±0.06 g/cm3(Predicted)
pka: -1.39±0.50(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-(3,4-dichlorophenyl)-N-methylpropionamide Chemical Properties,Usage,Production

Uses

ELP-004 is a TRPC channel inhibitor and inhibtis TRPC channel-mediated Ca2+ entry. ELP-004 is an osteoclast inhibitor and inhibits osteoclast differentiation. ELP-004 inhibits basal Ca2+ and related NFATc1 translocation in inflammatory osteoclastogenesis. ELP-004 reduces bone erosion in a mouse model of rheumatoid arthritis[1][2].

References

[1] Ray S, et al. Targeting TRPC channels for control of arthritis-induced bone erosion. Sci Adv. 2025 Jan 17;11(3):eabm9843. DOI:10.1126/sciadv.abm9843
[2] McCall JL, et al. Preclinical evaluation of ELP-004 in mice. Pharmacol Res Perspect. 2024 Aug;12(4):e1230. DOI:10.1002/prp2.1230

N-(3,4-dichlorophenyl)-N-methylpropionamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(3,4-dichlorophenyl)-N-methylpropionamide Suppliers

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15533-81-0, N-(3,4-dichlorophenyl)-N-methylpropionamideRelated Search:

N-(3,4-dichlorophenyl)-N-methylpropionamide

Propanamide, N-(3,4-dichlorophenyl)-N-methyl-

N-(3,4-dichlorophenyl)-N-methylpropanamide

ELP-004

15533-81-0