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ASP7663

Product Name
ASP7663
CAS No.
1190217-35-6
Chemical Name
ASP7663
Synonyms
ASP7663;ASP7663 >=98% (HPLC);ASP7663, 10 mM in DMSO;ASP 7663;ASP-7663;ASP7663;(E)-2-(7-Fluoro-1-isobutyl-2-oxoindolin-3-ylidene)acetic acid;(2E)-2-[7-Fluoro-1,2-dihydro-1-(2-methylpropyl)-2-oxo-3H-indol-3-ylidene]acetic acid;Acetic acid, 2-[7-fluoro-1,2-dihydro-1-(2-methylpropyl)-2-oxo-3H-indol-3-ylidene]-, (2E)-;pain,ASP-7663,inhibit,TRP Channel,ASP7663,Transient receptor potential channels,Inhibitor,ASP 7663
CBNumber
CB03959569
Molecular Formula
C14H14FNO3
Formula Weight
263.26
MOL File
1190217-35-6.mol
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ASP7663 Property

storage temp. 
Store at -20°C
solubility 
DMSO: 25 mg/ml,Ethanol: 25 mg/ml
form 
A crystalline solid
color 
Light yellow to orange
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Tocris
Product number
5178
Product name
ASP7663
Purity
≥98%(HPLC)
Packaging
10
Price
$212
Updated
2021/12/16
Tocris
Product number
5178
Product name
ASP7663
Purity
≥98%(HPLC)
Packaging
50
Price
$887
Updated
2021/12/16
TRC
Product number
A780113
Product name
ASP7663
Packaging
1mg
Price
$110
Updated
2021/12/16
Usbiological
Product number
254683
Product name
ASP 7663
Packaging
10mg
Price
$460
Updated
2021/12/16
ChemScene
Product number
CS-0022157
Product name
ASP7663
Purity
99.16%
Packaging
50mg
Price
$480
Updated
2021/12/16
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ASP7663 Chemical Properties,Usage,Production

Uses

ASP 7663 is a novel and selective transient receptor potential ankyrin 1 (TRPA1) agonist, which can be an effective anti-constipation drug with abdominal analgesic effect

Biological Activity

ASP7663 is a selective activator of transient receptor potential ankyrin 1 (TRPA1), known to play a role for chemical sensing in the pain pathway. ASP7663 activated human, rat, and mouse TRPA1 receptors with EC50 values of 510, 540, and 500 nM, respectively, and little or no affinity at more than 60 other related receptors, channels and enzymes. ASP7663 enhanced colonic motility and exerted analgesic effects against abdominal pain in mouse models.

storage

Store at +4°C

ASP7663 Preparation Products And Raw materials

Raw materials

Preparation Products

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ASP7663 Suppliers

China 41 United Kingdom 1 United States 8 USA 1 Global 51
Tocris Bioscience
Tel
--
Fax
--
Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77

1190217-35-6, ASP7663Related Search:


  • ASP7663
  • (2E)-2-[7-Fluoro-1,2-dihydro-1-(2-methylpropyl)-2-oxo-3H-indol-3-ylidene]acetic acid
  • ASP 7663;ASP-7663;ASP7663
  • Acetic acid, 2-[7-fluoro-1,2-dihydro-1-(2-methylpropyl)-2-oxo-3H-indol-3-ylidene]-, (2E)-
  • ASP7663 >=98% (HPLC)
  • pain,ASP-7663,inhibit,TRP Channel,ASP7663,Transient receptor potential channels,Inhibitor,ASP 7663
  • (E)-2-(7-Fluoro-1-isobutyl-2-oxoindolin-3-ylidene)acetic acid
  • ASP7663, 10 mM in DMSO
  • 1190217-35-6