ChemicalBook > CAS DataBase List > DM1-SPP
DM1-SPP
- Product Name
- DM1-SPP
- CAS No.
- 452072-20-7
- Chemical Name
- DM1-SPP
- Synonyms
- SPP-DM1;DM1-SPP;Maytansine, N2'-deacetyl-N2'-[3-[[4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1-methyl-4-oxobutyl]dithio]-1-oxopropyl]-
- CBNumber
- CB03959882
- Molecular Formula
- C44H59ClN4O14S2
- Formula Weight
- 967.54
- MOL File
- 452072-20-7.mol
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DM1-SPP Property
- Density
- 1.39±0.1 g/cm3(Predicted)
- pka
- 9.82±0.70(Predicted)
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0104940
- Product name
- SPP-DM1
- Packaging
- 50mg
- Price
- $8046
- Updated
- 2021/12/16
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DM1-SPP Chemical Properties,Usage,Production
Uses
SPP-DM1 is a agent-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker SPP[1].
IC 50
Maytansinoids
References
[1] Manu Lopus et al. Maytansine and Cellular Metabolites of Antibody-Maytansinoid Conjugates Strongly Suppress Microtubule Dynamics by Binding to Microtubules. DOI:10.1158/1535-7163.MCT-10-0644
DM1-SPP Preparation Products And Raw materials
Raw materials
Preparation Products
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DM1-SPP Suppliers
- Tel
- 15911056312
- liming@bio-fount.com
- Country
- China
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- +1-781-999-5354; +17819995354
- marketing@targetmol.com
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- United States
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- +1-631-485-4226
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- 1-631-614-7828
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- United States
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- 15002134094
- marketing@targetmol.cn
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- China
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- Tel
- 17688489295
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- CHINA
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