Synthesis

(4'-METHYLBIPHENYL-3-YL)-METHANOL

Synthesis
Product Name
(4'-METHYLBIPHENYL-3-YL)-METHANOL
CAS No.
89951-79-1
Chemical Name
(4'-METHYLBIPHENYL-3-YL)-METHANOL
Synonyms
AKOS BAR-1215;RARECHEM AL BD 1348;3-(4-Tolyl)benzyl alcohol;(4'-METHYLBIPHENYL-3-YL)-METHANOL;4'-Methyl[1,1'-biphenyl]-3-methanol;(4'-METHYL[1,1'-BIPHENYL]-3-YL)METHANOL;(4'-Methyl-[1,1'-biphenyl]-3-yl)methanol
CBNumber
CB0405788
Molecular Formula
C14H14O
Formula Weight
198.26
MOL File
89951-79-1.mol
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(4'-METHYLBIPHENYL-3-YL)-METHANOL Property

Boiling point:
346.3±11.0 °C(Predicted)
Density 
1.072±0.06 g/cm3(Predicted)
pka
14.31±0.10(Predicted)
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Safety

HS Code 
2905190098
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
M220768
Product name
(4''-Methyl-[1,1’-biphenyl]-3-yl)methanol
Packaging
50mg
Price
$45
Updated
2021/12/16
TRC
Product number
M220768
Product name
(4''-Methyl-[1,1’-biphenyl]-3-yl)methanol
Packaging
100mg
Price
$60
Updated
2021/12/16
ChemScene
Product number
CS-D0390
Product name
(4'-METHYL-[1,1'-BIPHENYL]-3-YL)METHANOL
Packaging
1g
Price
$70
Updated
2021/12/16
AK Scientific
Product number
AMTDA143
Product name
(4'-Methyl-[1,1'-biphenyl]-3-yl)methanol
Packaging
1g
Price
$70
Updated
2021/12/16
Apolloscientific
Product number
OR303368
Product name
(4'-Methyl-[1,1'-biphenyl]-3-yl)methanol
Packaging
500mg
Price
$95
Updated
2021/12/16
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(4'-METHYLBIPHENYL-3-YL)-METHANOL Chemical Properties,Usage,Production

Synthesis

To a suspension of potassium flfluoride (350 mg, 6.0 mmol, spray dried) in DMF (50 mL) were added ethyldiflfluoro-(4-methyl)silane (560 mg, 3.0 mmol), 3-iodobenzyl alcohol (250 mg, 2.0 mmol), and (η3 -C3H5PdCl)2 (37 mg, 0.1 mmol). The resulting mixture was stirred at 100 °C for 15 h, cooled to room temperature, poured into saturated aqueous sodium bicarbonate solution, and extracted with diethyl ether (3 × 20 mL). The combined ethereal layer was then dried over magnesium sulfate. The solvent was removed under reduced pressure. The crude material was purifified by silica gel chromatography eluting a mixture of hexane:EtOAc (5:1) to give 340 mg (86%) of 3-hydroxymethyl-4´-methylbiphenyl as a colorless solid.Reference: Hatanaka, Y; Goda, K.; Okahara, Y.; Hiyama, T. Tetrahedron 1994, 50, 8301−8316.

(4'-METHYLBIPHENYL-3-YL)-METHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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(4'-METHYLBIPHENYL-3-YL)-METHANOL Suppliers

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