6-METHYLBENZOTHIOPYRAN-4(4H)-ONE
- Product Name
- 6-METHYLBENZOTHIOPYRAN-4(4H)-ONE
- CAS No.
- 6948-34-1
- Chemical Name
- 6-METHYLBENZOTHIOPYRAN-4(4H)-ONE
- Synonyms
- Einecs 230-114-8;6-METHYLTHIOCHROMANONE;6-METHYLTHIOCHROMAN-4-ONE;6-methyl-4H-thiochromen-4-one;6-METHYLBENZOTHIOPRAN-4(4H)-ONE;6-METHYLBENZOTHIOPYRAN-4(4H)-ONE;6-methyl-2,3-dihydrothiochromen-4-one;6-Methylthiochroman-4-one in isooctane;3,4-Dihydro-6-methyl-2H-1-benzothiopyran-4-one;2,3-dihydro-6-methyl-4H-1-benzothiopyran-4-one
- CBNumber
- CB0408138
- Molecular Formula
- C10H10OS
- Formula Weight
- 178.25
- MOL File
- 6948-34-1.mol
6-METHYLBENZOTHIOPYRAN-4(4H)-ONE Property
- Melting point:
- 41-45 °C(lit.)
- Boiling point:
- 174 °C(Press: 10 Torr)
- Density
- 1.200±0.06 g/cm3(Predicted)
- Flash point:
- 110 °C
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- Light yellow to orange Solid
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- HS Code
- 2934999090
N-Bromosuccinimide Price
- Product number
- J98948
- Product name
- 6-Methylthiochroman-4-one
- Packaging
- 100mg
- Price
- $22
- Updated
- 2021/12/16
- Product number
- OR33257
- Product name
- 6-Methyl-3,4-dihydro-2H-1-benzothiopyran-4-one
- Purity
- 95%
- Packaging
- 1g
- Price
- $856
- Updated
- 2021/12/16
- Product number
- CHM0114975
- Product name
- 6-METHYLTHIOCHROMAN-4-ONE
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $584.55
- Updated
- 2021/12/16
- Product number
- CHM0114975
- Product name
- 6-METHYLTHIOCHROMAN-4-ONE
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $623.35
- Updated
- 2021/12/16
- Product number
- 6948341
- Product name
- 6-Methylthiochroman-4-one
- Packaging
- 10g
- Price
- $786.79
- Updated
- 2021/12/16
6-METHYLBENZOTHIOPYRAN-4(4H)-ONE Chemical Properties,Usage,Production
Synthesis
13739-35-0
6948-34-1
General procedure for the synthesis of 6-methylthiobenzodihydropyran-4-one from 3-[(4-methylphenyl)thio]propionic acid: 20 g (0.1 mol) of 3-[(4-methylphenyl)thio]propionic acid was dissolved in a 1000 ml beaker containing 70 ml of concentrated sulphuric acid, and the reaction was carried out for 12 h at room temperature. Upon completion of the reaction, the reaction mixture was cooled in an ice-water bath to precipitate a large amount of yellow solid precipitate, which was subsequently filtered. The filter cake was washed sequentially with 5% sodium bicarbonate solution and distilled water until neutral. The crude product was purified by recrystallization from 50% ethanol solution to give 16.88 g of light yellow solid 6-methylthiobenzodihydropyran-4-one in 93% yield.
References
[1] Letters in Organic Chemistry, 2016, vol. 13, # 3, p. 206 - 216
[2] Journal of Chemical Research, 2004, # 6, p. 394 - 395
[3] Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 13, p. 4569 - 4574
[4] Chinese Journal of Chemistry, 2011, vol. 29, # 4, p. 757 - 764
[5] Chemische Berichte, 1923, vol. 56, p. 1275
6-METHYLBENZOTHIOPYRAN-4(4H)-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
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