15-EPI PROSTAGLANDIN A1 Property

Boiling point:

510.7±50.0 °C(Predicted)

Density 

1.086±0.06 g/cm3(Predicted)

solubility 

DMF: >50 mg/ml; DMSO: >75 mg/ml; Ethanol: >100 mg/ml; PBS (pH 7.2): >2.4 mg/ml

pka

4.77±0.10(Predicted)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

H336May cause drowsiness or dizziness

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

15-EPI PROSTAGLANDIN A1 Chemical Properties,Usage,Production

Description

15-epi PGA₁ is the 15(R) stereoisomer of PGA₁. Prostaglandins of the A-series, including some with 15(R) stereochemistry, are natural products of gorgonian soft corals. PGA₁ causes renal vasodilation, increased urine sodium excretion, and decreased arterial pressure in hypertensive patients. There are no published reports on the biological activity of 15-epi PGA₁ at this time.

Uses

15-epi PGA1 is the 15(R) stereoisomer of PGA1. Prostaglandins of the A-series, including some with 15(R) stereochemistry, are natural products of gorgonian soft corals. PGA1 causes renal vasodilation, increased urine sodium excretion, and decreased arterial pressure in hypertensive patients. There are no published reports on the biological activity of 15-epi PGA1 at this time.

Uses

15-epi Prostaglandin A1 is a naturally occurring prostaglandin used in hypertension studies.

Definition

ChEBI: 15-epi-PGA1 is a prostanoid.