N-METHYL-N-PHENYLCARBAMOYL CHLORIDE Property

Melting point:

87-90 °C (lit.)

Boiling point:

280 °C (lit.)

Density 

1.1885 (rough estimate)

refractive index 

1.5430 (estimate)

storage temp. 

2-8°C

pka

0.06±0.50(Predicted)

CAS DataBase Reference

4285-42-1

EPA Substance Registry System

Carbamic chloride, methylphenyl- (4285-42-1)

Safety

Hazard Codes 

C

Risk Statements 

34-36/37

Safety Statements 

26-27-28-36/37/39-45

RIDADR 

UN 3261 8/PG 2

WGK Germany 

3

HS Code 

29242998

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

N-METHYL-N-PHENYLCARBAMOYL CHLORIDE Chemical Properties,Usage,Production

Chemical Properties

light yellow to light green crystalline mass or

Uses

N-Methyl-N-phenylcarbamoyl Chloride is a reagent for the preparation of carbamoylcholine analogs as it has biological activity as nicotinic acetylcholine receptor agonists.

General Description

Solvolyses of N-methyl-N-phenylcarbamoyl chlorides in aqueous binary mixtures of acetone, ethanol, methanol and in water, D₂O and 50% D₂O-CH₃OD were investigated. Iridium-catalyzed annulation of N-methyl-N-phenylcarbamoyl chloride with internal alkyne was reported.