ChemicalBook > CAS DataBase List > 1,3-Dihydro-2H-pyrrolo[3,2-b]pyridin-2-one

1,3-Dihydro-2H-pyrrolo[3,2-b]pyridin-2-one

Product Name
1,3-Dihydro-2H-pyrrolo[3,2-b]pyridin-2-one
CAS No.
32501-05-6
Chemical Name
1,3-Dihydro-2H-pyrrolo[3,2-b]pyridin-2-one
Synonyms
NSC 244253;4-Azaoxindole;4-Aza-2-oxindole;1H,3H-Pyrrolo[3,2-b]pyridin-2-one;1H,2H,3H-pyrrolo[3,2-b]pyridin-2-one;1,3-Dihydropyrrolo[3,2-b]pyridin-2-one;1,3-Dihydropyrrolo[3,2-b]pyridine-2-one;1,3-DIHYDRO-2H-PYRROLO[3,2-B]PYRIDIN-2-ONE;2H-Pyrrolo[3,2-b]pyridin-2-one, 1,3-dihydro-;1,3-Dihydro-2H-pyrrolo[3,2-b]pyridin-2-one ISO 9001：2015 REACH
CBNumber
CB0426589
Molecular Formula
C7H6N2O
Formula Weight
134.14
MOL File
32501-05-6.mol
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1,3-Dihydro-2H-pyrrolo[3,2-b]pyridin-2-one Property

Melting point:
204-206 °C
Boiling point:
336.9±37.0 °C(Predicted)
Density 
1.286±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
12.84±0.20(Predicted)
Appearance
Light brown to brown Solid
CAS DataBase Reference
32501-05-6
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
P840948
Product name
1H-Pyrrolo[3,2-B]pyridin-2(3H)-one
Packaging
10mg
Price
$45
Updated
2021/12/16
TRC
Product number
P840948
Product name
1H-Pyrrolo[3,2-B]pyridin-2(3H)-one
Packaging
50mg
Price
$65
Updated
2021/12/16
AK Scientific
Product number
3636AB
Product name
1H-Pyrrolo[3,2-b]pyridin-2(3H)-one
Packaging
100mg
Price
$96
Updated
2021/12/16
AK Scientific
Product number
3636AB
Product name
1H-Pyrrolo[3,2-b]pyridin-2(3H)-one
Packaging
250mg
Price
$126
Updated
2021/12/16
AK Scientific
Product number
3636AB
Product name
1H-Pyrrolo[3,2-b]pyridin-2(3H)-one
Packaging
1g
Price
$219
Updated
2021/12/16
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1,3-Dihydro-2H-pyrrolo[3,2-b]pyridin-2-one Chemical Properties,Usage,Production

Synthesis

295327-27-4

32501-05-6

General procedure for the synthesis of 4-azaindol-2-one from 2-(3-aminopyridin-2-yl)ethyl acetate: 2-(3-aminopyridin-2-yl)ethyl acetate (6.94 g, 0.038 mol) was dissolved in ether (100 mL) at room temperature. A 2 M hydrochloric acid solution (35 mL) was added slowly and the reaction mixture was stirred for 30 minutes. Subsequently, the volatile solvent was removed by rotary evaporation to give a brown solid product. This crude product was purified by recrystallization from a solvent mixture of ethanol and ether to give white crystals of 4-azaindol-2-one (4.0 g, 62% yield). The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 12.35 (s, 1H), 8.12 (m, 1H), 7.90 (m, 1H), 7.14 (m, 1H), 5.75 (s, 2H). Electrospray mass spectrometry (ESI-MS) showed the molecular ion peak m/z 135 ([M+H]+).

References

[1] Patent: US6369086, 2002, B1
[2] Patent: US6369086, 2002, B1
[3] Patent: US6624171, 2003, B1
[4] Patent: US6350747, 2002, B1. Location in patent: Page column 72
[5] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 4, p. 953 - 957

1,3-Dihydro-2H-pyrrolo[3,2-b]pyridin-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

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1,3-Dihydro-2H-pyrrolo[3,2-b]pyridin-2-one Suppliers

China 86 India 1 United States 11 Global 98
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View Lastest Price from 1,3-Dihydro-2H-pyrrolo[3,2-b]pyridin-2-one manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
1,3-Dihydro-2H-pyrrolo[3,2-b]pyridin-2-one 32501-05-6
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-13

32501-05-6, 1,3-Dihydro-2H-pyrrolo[3,2-b]pyridin-2-oneRelated Search:

Tetrahydropyran Pyrrolidine Polyvinylpyrrolidone Dihydromyrcenol N-Methyl-2-pyrrolidone Povidone iodine N-Vinyl-2-pyrrolidone METHYL-2-PYRROLIDONE GW441756 5-BROMO-1,3-DIHYDRO-2H-PYRROLO[3,2-B] PYRIDIN-2-ONE 5-METHOXY-4-AZA-2-OXINDOLE 1,3-DIHYDRO-3-[(1-METHYL-1H-INDOL-3-YL)METHYLENE]-2H-PYRROLO[3,2-B]PYRIDIN-2-ONE HYDROCHLORIDE 5-FLUORO-1,3-DIHYDRO-2H-PYRROLO[3,2-B] PYRIDIN-2-ONE 1H-Pyrrolo[3,2-b]pyridine-2,3-dione(9CI) 5-CHLORO-1,3-DIHYDRO-2H-PYRROLO[3,2-B] PYRIDIN-2-ONE 1,3-Dihydro-2H-pyrrolo[3,2-b]pyridin-2-one

  • 1,3-DIHYDRO-2H-PYRROLO[3,2-B]PYRIDIN-2-ONE
  • NSC 244253
  • 4-Aza-2-oxindole
  • 1,3-Dihydropyrrolo[3,2-b]pyridin-2-one
  • 1H,2H,3H-pyrrolo[3,2-b]pyridin-2-one
  • 1H,3H-Pyrrolo[3,2-b]pyridin-2-one
  • 4-Azaoxindole
  • 2H-Pyrrolo[3,2-b]pyridin-2-one, 1,3-dihydro-
  • 1,3-Dihydro-2H-pyrrolo[3,2-b]pyridin-2-one ISO 9001：2015 REACH
  • 1,3-Dihydropyrrolo[3,2-b]pyridine-2-one
  • 32501-05-6