1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE

Product Name: 1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE
CAS No.: 484-49-1
Chemical Name: 1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE
Synonyms: Olivacin;OLIVACINE;1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE;6H-Pyrido[4,3-B]carbazole, 1,5-dimethyl-;Inchi=1/C17H14N2/C1-10-12-7-8-18-11(2)14(12)9-15-13-5-3-4-6-16(13)19-17(10)15/H3-9,19H,1-2h
CBNumber: CB0434720
Molecular Formula: C17H14N2
Formula Weight: 246.31
MOL File: 484-49-1.mol

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1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE Property

Melting point:: 317-325°

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: PXT0001308
Product name: 1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE
Purity: 98.00%
Packaging: 25MG
Price: $1372.14
Updated: 2021/12/16

AHH

Product number: MT-11009
Product name: 1,5-Dimethyl-6H-pyrido[4,3-b]carbazole
Purity: 99%
Packaging: 1000g
Price: $495
Updated: 2021/12/16

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1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE Chemical Properties,Usage,Production

Description

This alkaloid has recently been shown to exhibit a marked antineoplastic activity. Administration of 25 or 50 mg/kg intraperitoneally on alternate days or daily until death to mice which had been inoculated with a single intraperitoneal dose of 106 -102 LI2l0 leukemia cells increased the survival time by 89-229 per cent compared with control animals.
Japanese workers have recently reported the synthesis of olivacine by heating indole with 4(1-hydroxyethyl)-3-methoxymethyl-2-methylpyridine in 47 per cent HBr.

Definition

ChEBI: Olivacine is a member of carbazoles.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 27, p. 1751, 1990 DOI: 10.1002/jhet.5570270645

References

Regina et al., Cienc. Cult. (Sao Paulo), 26, 517 (1974)
Synthesis: Kametani et al., J. Chern. Soc., Perkin I, 2102 (1975)

1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE Suppliers

China 1 South Korea 1 United Kingdom 3 United States 2 Global 7

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484-49-1, 1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLERelated Search:

1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE 2,4-dimethyl-6H-pyrido(3,2-b)carbazole 9-methoxy-1,5-dimethyl-6H-pyrido[4,3-b]carbazole 9-Bromo-5,11-dimethyl-6H-pyrido[4,3-b]carbazole 5,11-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE 1-chloro-9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole 2-benzyl-2,3,4,6-tetrahydro-9-methoxy-1,5-dimethyl-1H-pyrido[4,3-b]carbazole 9-Hydroxy-2-[2-(diethylamino)ethyl]-5,11-dimethyl-6H-pyrido[4,3-b]carbazole-2-ium 9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole

1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE

OLIVACINE

Olivacin

6H-Pyrido[4,3-B]carbazole, 1,5-dimethyl-

Inchi=1/C17H14N2/C1-10-12-7-8-18-11(2)14(12)9-15-13-5-3-4-6-16(13)19-17(10)15/H3-9,19H,1-2h

484-49-1

Indoles and derivatives