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Riluzole hydrochloride

Product Name
Riluzole hydrochloride
CAS No.
850608-87-6
Chemical Name
Riluzole hydrochloride
Synonyms
RILUZOLE HCL;RILUZOLE HYDROCHLORIDE;2-AMINO-6-TRIFLUOROMETHOXYBENZOTHIAZOLE HYDROCHLORIDE;6-(Trifluoromethoxy)benzo[d]thiazol-2-amine hydrochloride
CBNumber
CB0442491
Molecular Formula
C8H6ClF3N2OS
Formula Weight
270.66
MOL File
Mol file
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Riluzole hydrochloride Property

storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/mL; DMSO: 30 mg/mL; Ethanol: 30 mg/mL; Ethanol:PBS (pH7.2)(1:20): 0.04 mg/mL; Water: Soluble
form 
A solid
color 
White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
14577
Product name
Riluzole (hydrochloride)
Purity
≥99%
Packaging
10mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
14577
Product name
Riluzole (hydrochloride)
Purity
≥99%
Packaging
50mg
Price
$169
Updated
2024/03/01
Tocris
Product number
0768
Product name
Riluzolehydrochloride
Purity
≥98%(HPLC)
Packaging
25
Price
$106
Updated
2021/12/16
Usbiological
Product number
256455
Product name
Riluzole hydrochloride
Packaging
25mg
Price
$353
Updated
2021/12/16
TRC
Product number
R510030
Product name
RiluzoleHydrochloride
Packaging
250mg
Price
$580
Updated
2021/12/16
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Riluzole hydrochloride Chemical Properties,Usage,Production

Description

Riluzole is a benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na+ channels (ED50 = 2.3 μM). Riluzole suppresses glutamate-induced seizures in rats at an ED50 value of 3.2 mg/kg and displays neuroprotective effects in hypoxic animals at an ED50 value of 4 mg/kg. Formulations containing riluzole have been explored as therapeutics for slowing disease progression of amyotrophic lateral sclerosis.

Uses

Riluzole is a benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na+ channels (ED50 = 2.3 μM). Riluzole suppresses glutamate-induced seizures in rats at an ED50 value of 3.2 mg/kg and displays neuroprotective effects in hypoxic animals at an ED50 value of 4 mg/kg. Riluzole has been explored as a therapeutic for slowing disease progression of amyotrophic lateral sclerosis.

Uses

Riluzole is a glutamate release inhibitor. It also induces caspase-dependent apoptosis and suppress cell proliferation in human heptocellular carcinoma. Riluzole is a neuroprotective and a anticancer agent.

storage

Room temperature

Riluzole hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Riluzole hydrochloride Suppliers

China 27 United Kingdom 2 United States 6 USA 1 Global 36
3B Pharmachem (Wuhan) International Co.,Ltd.
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850608-87-6, Riluzole hydrochlorideRelated Search:

6-TRIFLUOROMETHOXYBENZOTHIAZOLE Riluzole

  • 2-AMINO-6-TRIFLUOROMETHOXYBENZOTHIAZOLE HYDROCHLORIDE
  • RILUZOLE HCL
  • RILUZOLE HYDROCHLORIDE
  • 6-(Trifluoromethoxy)benzo[d]thiazol-2-amine hydrochloride
  • 850608-87-6