METHYL 2-PYRIDYLACETATE
- Product Name
- METHYL 2-PYRIDYLACETATE
- CAS No.
- 1658-42-0
- Chemical Name
- METHYL 2-PYRIDYLACETATE
- Synonyms
- methyl 2-(pyridin-2-yl)acetate;METHYL 2-PYRIDINEACETATE;NSC 72093;METHYLPYRIDYL-2 ACETATE;METHYL 2-PYRIDYLACETATE;Methyl pyridine-2-acetate;Methyl 2-pyridinylacetate;Methyl2-Pyridylacetate>METHYL PYRIDIN-2-YLACETATE;Methyl 2-pyridylacetate,98%
- CBNumber
- CB0445922
- Molecular Formula
- C8H9NO2
- Formula Weight
- 151.16
- MOL File
- 1658-42-0.mol
METHYL 2-PYRIDYLACETATE Property
- Boiling point:
- 103 °C/0.5 mmHg (lit.)
- Density
- 1.119 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.506(lit.)
- Flash point:
- >230 °F
- storage temp.
- Inert atmosphere,Room Temperature
- form
- clear liquid
- pka
- 4.35±0.12(Predicted)
- color
- Light yellow to Amber to Dark green
- InChIKey
- ORAKNQSHWMHCEY-UHFFFAOYSA-N
- CAS DataBase Reference
- 1658-42-0
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M78305
- Product name
- Methyl 2-pyridylacetate
- Purity
- 98%
- Packaging
- 5g
- Price
- $78
- Updated
- 2023/06/20
- Product number
- M78305
- Product name
- Methyl 2-pyridylacetate
- Purity
- 98%
- Packaging
- 25g
- Price
- $370
- Updated
- 2023/06/20
- Product number
- P1268
- Product name
- Methyl 2-Pyridylacetate
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $68
- Updated
- 2025/07/31
- Product number
- P1268
- Product name
- Methyl 2-Pyridylacetate
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $204
- Updated
- 2025/07/31
- Product number
- M78305
- Product name
- Methyl 2-pyridylacetate
- Purity
- 98%
- Packaging
- 100g
- Price
- $714
- Updated
- 2023/01/07
METHYL 2-PYRIDYLACETATE Chemical Properties,Usage,Production
Chemical Properties
Clear yellow liquid
Synthesis
67-56-1
16179-97-8
1658-42-0
The general procedure for the synthesis of methyl 2-pyridylacetate from methanol and 2-pyridylacetic acid hydrochloride was as follows: the target compound was prepared by referring to literature methods. 2.00 g of 2-pyridine acetic acid hydrochloride (11.5 mmol, 1.00 eq.) was added to a round-bottom flask with 14 mL of methanol. The reaction system was cooled to 0 °C and 2.90 mL of trimethylchlorosilane (23.0 mmol, 2.00 eq.) was slowly added dropwise. After the dropwise addition, the reaction mixture was gradually warmed to room temperature and stirred overnight. After completion of the reaction, the solvent was removed by rotary evaporator under reduced pressure. The residual solid was neutralized by slowly adding 40 mL of saturated aqueous sodium bicarbonate solution to the residual solid. Subsequently, the aqueous phase was extracted with dichloromethane (4 x 40 mL), and the organic phase was combined and dried over anhydrous sodium sulfate. After filtration, the organic phase was concentrated under reduced pressure to afford the crude product methyl 2-pyridylacetate (1.73 g, 11.47 mmol, quantitative yield) as a clear oil. The structure of the product was confirmed by comparing the spectral data of the compound with data reported in the literature.
References
[1] Tetrahedron, 2011, vol. 67, # 24, p. 4435 - 4441
[2] Patent: WO2017/87667, 2017, A1. Location in patent: Paragraph 0069
[3] Journal of the American Chemical Society, 2015, vol. 137, # 32, p. 10246 - 10253
[4] Journal of Organic Chemistry, 2001, vol. 66, # 20, p. 6595 - 6603
METHYL 2-PYRIDYLACETATE Preparation Products And Raw materials
Raw materials
Preparation Products
METHYL 2-PYRIDYLACETATE Suppliers
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- --
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- info@acros.com
- Country
- Belgium
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View Lastest Price from METHYL 2-PYRIDYLACETATE manufacturers
- Product
- METHYL 2-PYRIDYLACETATE 1658-42-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-25
- Product
- METHYL 2-PYRIDYLACETATE 1658-42-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2019-05-24