ChemicalBook > CAS DataBase List > BIS(P-TOLYL)PHOSPHINE OXIDE

BIS(P-TOLYL)PHOSPHINE OXIDE

Product Name
BIS(P-TOLYL)PHOSPHINE OXIDE
CAS No.
2409-61-2
Chemical Name
BIS(P-TOLYL)PHOSPHINE OXIDE
Synonyms
Bis(p-toL;Di-p-tolylphosphine oxide;BIS(P-TOLYL)PHOSPHINE OXIDE;Di(p-tolyl)phosphineOxide>bis(4-methylphenyl)-oxophosphanium;Bis(4-Methylphenyl)phosphine Oxide;Bis (p-Methylphenyl) phosphine oxide;Phosphine oxide, bis(4-methylphenyl)-;1-Methyl-4-[(4-Methylphenyl)phosphoryl]benzene
CBNumber
CB0448246
Molecular Formula
C14H15OP
Formula Weight
230.24
MOL File
2409-61-2.mol
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BIS(P-TOLYL)PHOSPHINE OXIDE Property

Melting point:
96°C(lit.)
Boiling point:
354.2±45.0 °C(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
powder to crystal
color 
White to Almost white
Water Solubility 
Slightly soluble in water.
InChI
InChI=1S/C14H15OP/c1-11-3-7-13(8-4-11)16(15)14-9-5-12(2)6-10-14/h3-10,16H,1-2H3
InChIKey
GCUWBTGMXUIKOB-UHFFFAOYSA-N
SMILES
P(=O)(C1=CC=C(C)C=C1)C1=CC=C(C)C=C1
CAS DataBase Reference
2409-61-2
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Safety

Risk Statements 
20/21/22
Safety Statements 
26-36/37/39
HS Code 
29319090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
D4520
Product name
Di(p-tolyl)phosphine Oxide
Purity
>95.0%(GC)
Packaging
1g
Price
$100
Updated
2025/07/31
TCI Chemical
Product number
D4520
Product name
Di(p-tolyl)phosphine Oxide
Purity
>95.0%(GC)
Packaging
5g
Price
$301
Updated
2025/07/31
TRC
Product number
P769160
Product name
Bis(p-tolyl)phosphineoxide
Packaging
500mg
Price
$200
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB149535
Product name
Bis(p-tolyl)phosphineoxide
Packaging
2g
Price
$162
Updated
2021/12/16
Matrix Scientific
Product number
092402
Product name
Di-p-tolylphosphine oxide
Purity
95+%
Packaging
1g
Price
$189
Updated
2021/12/16
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BIS(P-TOLYL)PHOSPHINE OXIDE Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

Bis(p-tolyl)phosphine oxide is used as an organic chemical synthesis intermediate.

Uses

suzuki reaction

Synthesis Reference(s)

[1] Controllable Phosphorylation of Thioesters: Selective Synthesis of Aryl and Benzyl Phosphoryl Compounds. J. Org. Chem. 2020, 85, 22, 14653–14663.

Synthesis

A dried 250 mL flask was charge with p-tolylmagnesium bromide (33 mmol, 1.0 mol/L in THF) in an ice-water bath under N2. A solution of diethylphosphite (1.3 mL, 10.0 mmol) in anhydrous THF (5.0 mL) was then added dropwise over 30 min. The mixture was further stirred at ambient temperature overnight. After that, the reaction mixture was cooled to 0 °C again, and HCl (100 mL 0.1 N) was added dropwise. The mixture was extracted with dichloromethane (100 mL × 3), and the combined organic phase was washed with saturated NaCl solution, dried over anhydrous MgSO4, filtered, and concentrated in vacuo. The crude product was purified by column chromatography (EtOAc) to give the desired product BIS(P-TOLYL)PHOSPHINE OXIDE.

BIS(P-TOLYL)PHOSPHINE OXIDE Preparation Products And Raw materials

Raw materials

Ethanol Phosphorus trichloride 4-Bromotoluene Tetrahydrofuran Ethyl acetate Dichloromethane Magnesium Lithium

Preparation Products

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BIS(P-TOLYL)PHOSPHINE OXIDE Suppliers

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View Lastest Price from BIS(P-TOLYL)PHOSPHINE OXIDE manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
Bis(4-methylphenyl)phosphine oxide 2409-61-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-27
Shaanxi Dideu Medichem Co. Ltd
Product
Di(p-tolyl)phosphine Oxide 2409-61-2
Price
US $1.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2020-01-16
Career Henan Chemical Co
Product
BIS(P-TOLYL)PHOSPHINE OXIDE 2409-61-2
Price
US $1.00/KG
Min. Order
1G
Purity
99%
Supply Ability
1MT
Release date
2018-08-09

2409-61-2, BIS(P-TOLYL)PHOSPHINE OXIDERelated Search:

TRIS(4-METHYLPHENYL)PHOSPHINE OXIDE TRIS(4-(1H,1H,2H,2H-PERFLUORODECYL)-PHENYL)PHOSPHINE OXIDE BIS[4-(1H,1H,2H,2H-PERFLUORO-OCTYL)PHENYL]PHENYLPHOSPHINE OXIDE Bis(4-carboxyphenyl)phenyl-phosphine oxide TRIS[4-(PERFLUOROHEXYL)PHENYL]PHOSPHINE OXIDE TRIS(4-(1H,1H,2H,2H-PERFLUOROOCTYL)-PHENYL)PHOSPHINE OXIDE BIS[4-(1H,1H,2H,2H-PERFLUORODECYL)PHENYL]PHENYLPHOSPHINE OXIDE TRIS[4-(PERFLUOROOCTAL)PHENYL]PHOSPHINE OXIDE BIS(P-TOLYL)PHOSPHINE OXIDE

  • Bis(4-Methylphenyl)phosphine Oxide
  • Bis (p-Methylphenyl) phosphine oxide
  • Di-p-tolylphosphine oxide
  • BIS(P-TOLYL)PHOSPHINE OXIDE
  • 1-Methyl-4-[(4-Methylphenyl)phosphoryl]benzene
  • Bis(p-toL
  • bis(4-methylphenyl)-oxophosphanium
  • Di(p-tolyl)phosphineOxide&gt
  • Phosphine oxide, bis(4-methylphenyl)-
  • 2409-61-2