ChemicalBook > CAS DataBase List > DIETHYL 4-BROMOBENZYL PHOSPHONATE

DIETHYL 4-BROMOBENZYL PHOSPHONATE

Product Name
DIETHYL 4-BROMOBENZYL PHOSPHONATE
CAS No.
38186-51-5
Chemical Name
DIETHYL 4-BROMOBENZYL PHOSPHONATE
Synonyms
4-Bromobenzyl diethylphosphite;Diethy 4-Bromobenzyl Phosphonate;DIETHYL 4-BROMOBENZYL PHOSPHONATE;Diethyl(4-Bromobenzyl)phosphonate>4-BROMOBENZYL-PHOSPHONIC ACID DIETHYLESTER;Diethyl P-[(4-bromophenyl)methyl]phosphonate;Phosphonic acid, P-[(4-bromophenyl)methyl]-, diethyl ester
CBNumber
CB0455086
Molecular Formula
C11H16BrO3P
Formula Weight
307.12
MOL File
38186-51-5.mol
More
Less

DIETHYL 4-BROMOBENZYL PHOSPHONATE Property

Boiling point:
183 °C / 0.6mmHg
Density 
1.37
refractive index 
1.5230-1.5270
storage temp. 
Sealed in dry,Room Temperature
form 
clear liquid
color 
Colorless to Almost colorless
CAS DataBase Reference
38186-51-5
More
Less

Safety

HS Code 
2931.90.6000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
D3688
Product name
Diethyl (4-Bromobenzyl)phosphonate
Purity
>98.0%(GC)
Packaging
5g
Price
$41
Updated
2025/07/31
TCI Chemical
Product number
D3688
Product name
Diethyl (4-Bromobenzyl)phosphonate
Purity
>98.0%(GC)
Packaging
25g
Price
$162
Updated
2025/07/31
TRC
Product number
D443855
Product name
Diethyl (4-Bromobenzyl)phosphonate
Packaging
500mg
Price
$85
Updated
2021/12/16
TRC
Product number
D443855
Product name
Diethyl (4-Bromobenzyl)phosphonate
Packaging
5g
Price
$415
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
ING0006028
Product name
DIETHY 4-BROMOBENZYLPHOSPHONATE
Purity
95.00%
Packaging
5G
Price
$540
Updated
2021/12/16
More
Less

DIETHYL 4-BROMOBENZYL PHOSPHONATE Chemical Properties,Usage,Production

Chemical Properties

Colorless liquid

Uses

Diethyl 4-Bromobenzylphosphonate can be used as a virucide.

Synthesis

589-15-1

122-52-1

38186-51-5

General procedure for the synthesis of diethyl 4-bromobenzylphosphonate (16) from p-bromobenzyl bromide and triethyl phosphite: 1-bromo-4-(bromomethyl)benzene (5.0 g, 20 mmol) and triethyl phosphite (51 mL, 300 mmol) were added to a round-bottomed flask, and the mixture was reacted by refluxing the reaction for 19 hours at 90 °C. Upon completion of the reaction, the excess triethyl phosphite was removed by distillation under reduced pressure. The crude product was purified by fast column chromatography (eluent ratio 1:1 hexane/ethyl acetate) to afford the target compound 16 in 98% yield. The product was a colorless liquid; 1H NMR (400 MHz, CDCl3) δ 7.30 (d, 2H, J = 7.5 Hz), 7.05 (d, 2H, J = 7.6 Hz), 3.99-3.88 (m, 4H), 2.99 (s, 1H), 2.94 (s, 1H), 1.12 (t, 6H, J = 6.9 Hz); 13C NMR ( 100 MHz, CDCl3) δ 131.7, 131.6, 131.5, 121.0, 62.3, 34.0, 32.0, 16.5; HRMS calculated value (C11H16BrO3P, [M + H]+) 307.0097, measured value 307.0093.

References

[1] Patent: US6689922, 2004, B1. Location in patent: Page column 23
[2] Chemistry - A European Journal, 2012, vol. 18, # 24, p. 7473 - 7485
[3] Synthetic Communications, 2011, vol. 41, # 2, p. 206 - 218
[4] Patent: US2013/41153, 2013, A1. Location in patent: Paragraph 0041; 0042; 0043; 0044
[5] ChemMedChem, 2010, vol. 5, # 1, p. 56 - 60

DIETHYL 4-BROMOBENZYL PHOSPHONATE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

DIETHYL 4-BROMOBENZYL PHOSPHONATE Suppliers

Americas 1 China 97 Europe 1 France 2 Germany 1 India 3 Japan 1 The Netherlands 1 United Kingdom 4 United States 10 Global 121
TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23653
Advantage
75
More
Less

View Lastest Price from DIETHYL 4-BROMOBENZYL PHOSPHONATE manufacturers

Career Henan Chemical Co
Product
DIETHYL 4-BROMOBENZYL PHOSPHONATE 38186-51-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-31

38186-51-5, DIETHYL 4-BROMOBENZYL PHOSPHONATERelated Search:

Diethyl 3,5-Dimethoxybenzylphosphonate DIETHYL 4-METHOXYBENZYLPHOSPHONATE Diethyl 2-broMobenzylphosphonate 2-methoxy-1-diethylphosphonomethyl-benzene DIETHYL(4-NITROBENZYL)PHOSPHONATE Diethyl 2-chlorobenzylphosphonate 2-Iodobenzylphosphonsaeurediethylester (3-METHOXYBENZYL)PHOSPHONIC ACID DIETHYL ESTER DIMETHYL(4-METHOXYBENZYL)PHOSPHONATE (3-CHLOROBENZYL)PHOSPHONIC ACID DIETHYL ESTER DiMethyl 2-(1,3-Dithiole)phosphonate DIMETHYL(4-BROMOBENZYL)PHOSPHONATE diethyl 2-nitrobenzylphosphonate DIETHYL 4-BROMOBENZYL PHOSPHONATE Diethyl phosphite (4-BROMOBENZYL)PHOSPHONIC ACID DIISOPROPYL ANILINO(4-BROMOPHENYL)METHYLPHOSPHONATE ZERENEX ZX000778

  • DIETHYL 4-BROMOBENZYL PHOSPHONATE
  • 4-BROMOBENZYL-PHOSPHONIC ACID DIETHYLESTER
  • Diethy 4-Bromobenzyl Phosphonate
  • Diethyl(4-Bromobenzyl)phosphonate&gt
  • Phosphonic acid, P-[(4-bromophenyl)methyl]-, diethyl ester
  • 4-Bromobenzyl diethylphosphite
  • Diethyl P-[(4-bromophenyl)methyl]phosphonate
  • 38186-51-5
  • C11H16BrO3P
  • Piperidines ,Homopiperidines
  • Horner-Emmons Reaction
  • Synthetic Organic Chemistry
  • Wittig & Horner-Emmons Reaction