ChemicalBook > CAS DataBase List > LY-3154207
LY-3154207
- Product Name
- LY-3154207
- CAS No.
- 1638667-79-4
- Chemical Name
- LY-3154207
- Synonyms
- mevidalen;LY-3154207;LY-3154207,LY3154207;Ethanone, 2-(2,6-dichlorophenyl)-1-[(1S,3R)-3,4-dihydro-3-(hydroxymethyl)-5-(3-hydroxy-3-methylbutyl)-1-methyl-2(1H)-isoquinolinyl]-;2-(2,6-dichlorophenyl)-1-((1S,3R)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one;2-(2,6-Dichlorophenyl)-1-((1S,3R)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one , LY3154207
- CBNumber
- CB04664136
- Molecular Formula
- C24H29Cl2NO3
- Formula Weight
- 450.4
- MOL File
- 1638667-79-4.mol
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LY-3154207 Property
- Boiling point:
- 628.4±55.0 °C(Predicted)
- Density
- 1.245±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 110 mg/mL (244.23 mM; Need ultrasonic)
- pka
- 14.60±0.10(Predicted)
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0105102
- Product name
- LY3154207
- Purity
- 99.81%
- Packaging
- 5mg
- Price
- $480
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0105102
- Product name
- LY3154207
- Purity
- 99.81%
- Packaging
- 10mg
- Price
- $800
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0105102
- Product name
- LY3154207
- Purity
- 99.81%
- Packaging
- 50mg
- Price
- $2250
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0105102
- Product name
- LY3154207
- Purity
- 99.81%
- Packaging
- 100mg
- Price
- $3250
- Updated
- 2021/12/16
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LY-3154207 Chemical Properties,Usage,Production
Uses
LY3154207 is a potent, subtype selective, and orally available human dopamine D1 receptor positive allosteric modulator (PAM) with minimal allosteric agonist activity (EC50=3 nM)[1].
References
[1] Hao J, Synthesis and Pharmacological Characterization of 2-(2,6-Dichlorophenyl)-1-((1S,3R)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one (LY3154207), a Potent, Subtype Selective, and Orally Available Po DOI:10.1021/acs.jmedchem.9b01234
LY-3154207 Preparation Products And Raw materials
Raw materials
Preparation Products
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