Rp-8-bromo-Cyclic AMPS (sodium salt)
- Product Name
- Rp-8-bromo-Cyclic AMPS (sodium salt)
- CAS No.
- 925456-59-3
- Chemical Name
- Rp-8-bromo-Cyclic AMPS (sodium salt)
- Synonyms
- Rp-isomer;Rp-8-bromo-cAMPS;8-Bromoadenosine 3';Rp-8-bromo-Cyclic AMPS;5'-cyclic monophosphorothioate;Rp-8-bromo-Cyclic AMPS (sodium salt);8-bromo-adenosinecyclic3',5'-[hydrogen[P(R)]-phosphorothioate],monosodiumsalt;RP-8-BR-CAMPS;8-BROMOADENOSINE 3';5'-CYCLIC MONOPHOSPHOROTHIOATE; RP-ISOMER;RP-8-BROMO-CAMPS;925456-59-3
- CBNumber
- CB04666286
- Molecular Formula
- C10H12BrN5NaO5PS
- Formula Weight
- 448.16
- MOL File
- 925456-59-3.mol
Rp-8-bromo-Cyclic AMPS (sodium salt) Property
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 0.5 mg/ml; PBS (pH 7.2): 10 mg/ml
- form
- A crystalline solid
N-Bromosuccinimide Price
- Product number
- 21584
- Product name
- Rp-8-bromo-Cyclic AMPS (sodium salt)
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $175
- Updated
- 2024/03/01
- Product number
- 21584
- Product name
- Rp-8-bromo-Cyclic AMPS (sodium salt)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $263
- Updated
- 2024/03/01
- Product number
- 21584
- Product name
- Rp-8-bromo-Cyclic AMPS (sodium salt)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $963
- Updated
- 2024/03/01
- Product number
- orb573125
- Product name
- Rp-8-bromo-Cyclic AMPS
- Purity
- >98%
- Packaging
- 10mg
- Price
- $1504.5
- Updated
- 2021/12/16
- Product number
- orb573125
- Product name
- Rp-8-bromo-Cyclic AMPS
- Purity
- >98%
- Packaging
- 20mg
- Price
- $2468.4
- Updated
- 2021/12/16
Rp-8-bromo-Cyclic AMPS (sodium salt) Chemical Properties,Usage,Production
Description
Rp-8-bromo-Cyclic AMPS (Rp-8-bromo-cAMPS) is a cell-permeable cAMP analog that combines an exocyclic sulfur substitution in the equatorial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP.1,2 It acts as an antagonist of cAMP-dependent protein kinases (PKAs) and is resistant to hydrolysis by cyclic nucleotide phosphodiesterases. Rp-8-bromo-cAMPS more effectively antagonizes cAMP-dependent activation of purified PKA type I from rabbit muscle than PKA type II from bovine heart.2
References
1. Dostmann, W.R., Taylor, S.S., Genieser, H.G., et al. Probing the cyclic nucleotide binding sites of cAMP-
2. Gjertsen, B.T., Mellgran, G., Otten, A., et al. Novel (Rp)-
Rp-8-bromo-Cyclic AMPS (sodium salt) Preparation Products And Raw materials
Raw materials
Preparation Products
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