ChemicalBook > CAS DataBase List > LDN-192960 (hydrochloride)

LDN-192960 (hydrochloride)

Product Name
LDN-192960 (hydrochloride)
CAS No.
2309172-48-1
Chemical Name
LDN-192960 (hydrochloride)
Synonyms
LDN-192960 (hydrochloride);LDN192960 hydrochloride,LDN 192960 hydrochloride;3-[(2,7-Dimethoxyacridin-9-yl)thio]-1-propanamine Dihydrochloride
CBNumber
CB04666529
Molecular Formula
C18H21ClN2O2S
Formula Weight
364.89
MOL File
2309172-48-1.mol
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LDN-192960 (hydrochloride) Property

storage temp. 
Store at -20°C
solubility 
DMSO:20.07(Max Conc. mg/mL);50.01(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);24.92(Max Conc. mM)
form 
A crystalline solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
19089
Product name
LDN-192960 (hydrochloride)
Purity
≥98%
Packaging
5mg
Price
$97
Updated
2024/03/01
Cayman Chemical
Product number
19089
Product name
LDN-192960 (hydrochloride)
Purity
≥98%
Packaging
10mg
Price
$184
Updated
2024/03/01
Cayman Chemical
Product number
19089
Product name
LDN-192960 (hydrochloride)
Purity
≥98%
Packaging
25mg
Price
$410
Updated
2024/03/01
Cayman Chemical
Product number
19089
Product name
LDN-192960 (hydrochloride)
Purity
≥98%
Packaging
50mg
Price
$768
Updated
2024/03/01
ChemScene
Product number
CS-0102845
Product name
LDN-192960(hydrochloride)
Purity
≥98.0%
Packaging
10mg
Price
$550
Updated
2021/12/16
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LDN-192960 (hydrochloride) Chemical Properties,Usage,Production

Uses

LDN-192960 hydrochloride is an inhibitor of Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC50s of 10 nM and 48 nM, respectively[1].

IC 50

DYRK1; DYRK2

References

[1] Cuny GD, et al. Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3491-4. PMID:20836251
[2] Gregory D Cuny, et al. Structure-activity Relationship Study of Acridine Analogs as Haspin and DYRK2 Kinase Inhibitors. Bioorg Med Chem Lett DOI:10.2174/0929867324666170414155520

LDN-192960 (hydrochloride) Preparation Products And Raw materials

Raw materials

Preparation Products

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LDN-192960 (hydrochloride) Suppliers

Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
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Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
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5132
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58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
Aikon International Limited
Tel
025-58859352 18921922613
Email
hywu@aikonchem.com
Country
China
ProdList
10709
Advantage
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Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
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Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Email
syeu@accelachem.com
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China
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RD International Technology Co., Limited
Tel
18024082417
Email
market@ubiochem.com
Country
China
ProdList
9835
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Cayman Chemical Company
Tel
800-364-9897
Email
sales@caymanchem.com
Country
China
ProdList
6838
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58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
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China
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Adooq Bioscience LLC
Tel
400-025-6535
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sales@adooq.cn
Country
China
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Guangzhou Haotian Biotechnology Co., Ltd.
Tel
15571990006
Country
CHINA
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Guangzhou Junze Biotechnology Co., Ltd.
Tel
17688489295
Country
CHINA
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Neobioscience Co., Ltd.
Tel
--
Fax
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Email
info@neobioscience.com
Country
CHINA
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6207
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Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
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Email
info@zzsrm.com
Country
CHINA
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2309172-48-1, LDN-192960 (hydrochloride)Related Search:


  • LDN-192960 (hydrochloride)
  • LDN192960 hydrochloride,LDN 192960 hydrochloride
  • 3-[(2,7-Dimethoxyacridin-9-yl)thio]-1-propanamine Dihydrochloride
  • 2309172-48-1