ChemicalBook > CAS DataBase List > GNE-781

GNE-781

Product Name
GNE-781
CAS No.
1936422-33-1
Chemical Name
GNE-781
Synonyms
GNE-781;GNE-781,Histone Acetyltransferase,Inhibitor,HATs,Epigenetic Reader Domain,GNE 781,HAT,inhibit,GNE781;3- (7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3.4-dihydro-2H-quinohn-1-yl]-N-methyl-1-(oxan-4-yl)-6,7-dihydro-4H-pyrazolo[4.3-c]pyridine-5-carboxamide;3-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-N-methyl-1-(tetrahydro-2H-pyran-4-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide;5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-1,4,6,7-tetrahydro-N-methyl-1-(tetrahydro-2H-pyran-4-yl)-
CBNumber
CB04667955
Molecular Formula
C27H33F2N7O2
Formula Weight
525.59
MOL File
1936422-33-1.mol
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GNE-781 Property

Melting point:
135-140oC
Boiling point:
800.7±65.0 °C(Predicted)
Density 
1.45±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
14.19±0.20(Predicted)
form 
Solid
color 
White to Pale Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D447825
Product name
GNE-781
Packaging
5mg
Price
$1465
Updated
2021/12/16
ChemScene
Product number
CS-0030034
Product name
GNE-781
Purity
98.19%
Packaging
100mg
Price
$3350
Updated
2021/12/16
ChemScene
Product number
CS-0030034
Product name
GNE-781
Purity
98.19%
Packaging
5mg
Price
$450
Updated
2021/12/16
ChemScene
Product number
CS-0030034
Product name
GNE-781
Purity
98.19%
Packaging
10mg
Price
$750
Updated
2021/12/16
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GNE-781 Chemical Properties,Usage,Production

Uses

GNE-781 is a highly advanced, potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein, binding protein (CBP). Inhibition of the bromodomain of the transcriptional regulator CBP/P300 is an especially interesting new therapeutic approach in oncology.

GNE-781 Preparation Products And Raw materials

Raw materials

Preparation Products

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GNE-781 Suppliers

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1936422-33-1, GNE-781Related Search:


  • GNE-781
  • 5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-1,4,6,7-tetrahydro-N-methyl-1-(tetrahydro-2H-pyran-4-yl)-
  • 3-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-N-methyl-1-(tetrahydro-2H-pyran-4-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide
  • 3- (7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3.4-dihydro-2H-quinohn-1-yl]-N-methyl-1-(oxan-4-yl)-6,7-dihydro-4H-pyrazolo[4.3-c]pyridine-5-carboxamide
  • GNE-781,Histone Acetyltransferase,Inhibitor,HATs,Epigenetic Reader Domain,GNE 781,HAT,inhibit,GNE781
  • 1936422-33-1
  • 1396422-33-1
  • C27H33F2N7O2