ChemicalBook > CAS DataBase List > KEA1-97

KEA1-97

Product Name
KEA1-97
CAS No.
2138882-71-8
Chemical Name
KEA1-97
Synonyms
KEA1-97;KEA1-97 >=98% (HPLC);4,6-Dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine;4,6-Dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine;1,3,5-Triazin-2-amine, 4,6-dichloro-N-(4'-fluoro[1,1'-biphenyl]-4-yl)-;Apoptosis,KEA1 97,Proliferation,Apoptotic,Caspase,inhibit,KEA-1-97,DCTalkyne,KEA1-97,231MFP,Inhibitor,Selective,KEA197
CBNumber
CB04668109
Molecular Formula
C15H9Cl2FN4
Formula Weight
335.16
MOL File
2138882-71-8.mol
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KEA1-97 Property

Boiling point:
530.3±52.0 °C(Predicted)
Density 
1.466±0.06 g/cm3(Predicted)
storage temp. 
4°C, protect from light
solubility 
DMSO : 100 mg/mL (298.36 mM; Need ultrasonic)
pka
0.57±0.10(Predicted)
form 
Solid
color 
White to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2180
Product name
KEA1-97
Purity
≥98% (HPLC)
Packaging
5mg
Price
$102
Updated
2024/03/01
Sigma-Aldrich
Product number
SML2180
Product name
KEA1-97
Purity
≥98% (HPLC)
Packaging
25mg
Price
$329
Updated
2024/03/01
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KEA1-97 Chemical Properties,Usage,Production

Description

KEA1-97 is a Thioredoxin-Caspase 3 interaction disruptor. It was found to target lysine 72 of thioredoxin, inhibiting its interactions with caspase 3 and inducing apoptosis without affecting other thioredoxin activity. KEA1-97 induced apoptosis in breast cancer cells and treatment of immune-deficient SCID mice at 5 mg/kg ip impaired breast tumor xenograft growth.

KEA1-97 Preparation Products And Raw materials

Raw materials

Preparation Products

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KEA1-97 Suppliers

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2138882-71-8, KEA1-97Related Search:


  • KEA1-97
  • 1,3,5-Triazin-2-amine, 4,6-dichloro-N-(4'-fluoro[1,1'-biphenyl]-4-yl)-
  • KEA1-97 >=98% (HPLC)
  • 4,6-Dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine
  • Apoptosis,KEA1 97,Proliferation,Apoptotic,Caspase,inhibit,KEA-1-97,DCTalkyne,KEA1-97,231MFP,Inhibitor,Selective,KEA197
  • 4,6-Dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine
  • 2138882-71-8
  • C15H9Cl2FN4