ChemicalBook > CAS DataBase List > KEA1-97
KEA1-97
- Product Name
- KEA1-97
- CAS No.
- 2138882-71-8
- Chemical Name
- KEA1-97
- Synonyms
- KEA1-97;KEA1-97 >=98% (HPLC);4,6-Dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine;4,6-Dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine;1,3,5-Triazin-2-amine, 4,6-dichloro-N-(4'-fluoro[1,1'-biphenyl]-4-yl)-;Apoptosis,KEA1 97,Proliferation,Apoptotic,Caspase,inhibit,KEA-1-97,DCTalkyne,KEA1-97,231MFP,Inhibitor,Selective,KEA197
- CBNumber
- CB04668109
- Molecular Formula
- C15H9Cl2FN4
- Formula Weight
- 335.16
- MOL File
- 2138882-71-8.mol
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KEA1-97 Property
- Boiling point:
- 530.3±52.0 °C(Predicted)
- Density
- 1.466±0.06 g/cm3(Predicted)
- storage temp.
- 4°C, protect from light
- solubility
- DMSO : 100 mg/mL (298.36 mM; Need ultrasonic)
- pka
- 0.57±0.10(Predicted)
- form
- Solid
- color
- White to light yellow
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML2180
- Product name
- KEA1-97
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $102
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- SML2180
- Product name
- KEA1-97
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $329
- Updated
- 2024/03/01
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KEA1-97 Chemical Properties,Usage,Production
Description
KEA1-97 is a Thioredoxin-Caspase 3 interaction disruptor. It was found to target lysine 72 of thioredoxin, inhibiting its interactions with caspase 3 and inducing apoptosis without affecting other thioredoxin activity. KEA1-97 induced apoptosis in breast cancer cells and treatment of immune-deficient SCID mice at 5 mg/kg ip impaired breast tumor xenograft growth.
KEA1-97 Preparation Products And Raw materials
Raw materials
Preparation Products
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