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4-(2-THIAZOLYL)PHENOL

Product Name
4-(2-THIAZOLYL)PHENOL
CAS No.
81015-49-8
Chemical Name
4-(2-THIAZOLYL)PHENOL
Synonyms
4-(2-Thiazolyl);4-(2-THIAZOLYL)PHENOL;4-(2-Thiazolyl)phenol8;Phenol, 4-(2-thiazolyl)-;4-(2-Thiazolyl)phenol95%;4-(2-THIAZOLYL)PHENOL 95%;4-(1,3-Thiazol-2-yl)phenol;2-(4-chlorophenyl)thiazole;4-(3H-1,3-thiazol-2-ylidene)cyclohexa-2,5-dien-1-one
CBNumber
CB0466905
Molecular Formula
C9H7NOS
Formula Weight
177.22
MOL File
81015-49-8.mol
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4-(2-THIAZOLYL)PHENOL Property

Melting point:
162-165℃
storage temp. 
Store at room temperature
Appearance
Light yellow to yellow Solid
CAS DataBase Reference
81015-49-8
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Safety

HS Code 
2934100090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
T430125
Product name
4-(2-Thiazolyl)phenol
Packaging
25mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
W8566
Product name
4-(2-Thiazolyl)phenol
Packaging
100mg
Price
$95
Updated
2021/12/16
Apolloscientific
Product number
OR913227
Product name
4-(2-Thiazolyl)phenol
Purity
95%
Packaging
1g
Price
$115
Updated
2021/12/16
Matrix Scientific
Product number
071922
Product name
4-(2-Thiazolyl)phenol
Purity
95+%
Packaging
1g
Price
$347
Updated
2021/12/16
Apolloscientific
Product number
OR913227
Product name
4-(2-Thiazolyl)phenol
Purity
95%
Packaging
5g
Price
$395
Updated
2021/12/16
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4-(2-THIAZOLYL)PHENOL Chemical Properties,Usage,Production

Synthesis

27088-84-2

81015-49-8

Step 2: Synthesis of 4-thiazol-2-yl-phenol; Boron tribromide (2.00 ml, 15.7 mmol) was added slowly and dropwise to a solution of dichloromethane (25 ml) of the product obtained in step 1 (1.0 g, 5.23 mmol) at -78 °C, keeping the temperature at -78 °C and stirring the reaction for 1 hour. Subsequently, the reaction mixture was warmed to room temperature and stirring was continued for 16 hours. After completion of the reaction, the reaction was quenched by slowly pouring the mixture into ice water. The solid product was collected by filtration and washed with ether to give the final target product 4-thiazol-2-yl-phenol (0.84 g, 84% yield); 1H NMR (400 MHz, CDCl3) δ 7.85 (d, J = 3.2Hz, 1H), 7.79 (d, J = 8.8Hz, 2H), 7.67 (d, J = 3.2Hz, 1H), 7.67 (d, J = 3.2Hz, 1H), 7.67 (d, J = 3.2Hz, 1H), and 6.88 (d, J = 8.8 Hz, 2H); MS (ESI-) m/z 176 ([M-H]-, 100).

References

[1] European Journal of Medicinal Chemistry, 2010, vol. 45, # 6, p. 2299 - 2306
[2] Patent: US2007/66820, 2007, A1. Location in patent: Page/Page column 78
[3] Patent: US2008/33024, 2008, A1. Location in patent: Page/Page column 7; 16
[4] Journal of Medicinal Chemistry, 1986, vol. 29, # 6, p. 1065 - 1080
[5] Journal of the American Chemical Society, 1930, vol. 52, p. 1585

4-(2-THIAZOLYL)PHENOL Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(2-THIAZOLYL)PHENOL Suppliers

China 55 Germany 1 India 2 United Kingdom 2 United States 7 Global 67
Alfa Aesar
Tel
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Fax
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Email
tech@alfa.com
Country
India
ProdList
6905
Advantage
58
A.J Chemicals
Tel
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Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
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81015-49-8, 4-(2-THIAZOLYL)PHENOLRelated Search:

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