SRT3025 Hydrochloride

Product Name: SRT3025 Hydrochloride
CAS No.: 2070015-26-6
Chemical Name: SRT3025 Hydrochloride
Synonyms: SRT3025 Hydrochloride;SIRTUIN MODULATOR 1;SRT3025 HCL;Inhibitor,Sirtuin,Sirtuin modulator1,inhibit,Sirtuin modulator-1,Sirtuin modulator 1;5-(3-Methoxypropyl)-2-phenyl-N-(2-(6-(pyrrolidin-1-ylmethyl)thiazolo[5,4-b]pyridin-2-yl)phenyl)thiazole-4-carboxamide hydrochloride
CBNumber: CB04672236
Molecular Formula: C31H32ClN5O2S2
Formula Weight: 606.2
MOL File: 2070015-26-6.mol

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SRT3025 Hydrochloride Property

storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: DMSO:56.25(Max Conc. mg/mL);92.79(Max Conc. mM)
Ethanol:5.0(Max Conc. mg/mL);8.25(Max Conc. mM)
form: A solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML3397
Product name: SRT3025 hydrochloride
Purity: ≥98% (HPLC)
Packaging: 10 mg
Price: $103.55
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML3397
Product name: SRT3025 hydrochloride
Purity: ≥98% (HPLC)
Packaging: 50 mg
Price: $439
Updated: 2025/07/31

TRC

Product number: S490940
Product name: SRT3025Hydrochloride
Packaging: 1mg
Price: $180
Updated: 2021/12/16

AK Scientific

Product number: 6186EF
Product name: SRT3025Hydrochloride
Packaging: 5mg
Price: $190
Updated: 2021/12/16

ChemScene

Product number: CS-5444
Product name: Sirtuinmodulator1
Purity: 99.44%
Packaging: 10mg
Price: $225
Updated: 2021/12/16

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SRT3025 Hydrochloride Chemical Properties,Usage,Production

Uses

SRT3025 Hydrochloride is a SIRT1 activator which in turn inhibits RANKL-induced osteoclastogenesis in bone marrow-derived macrophages. Decreases osteoclast-mediated bone resporption.

Biological Activity

SRT3025 is an orally active sirtuin 1 activator (Sirt1 EC1.5 ≤1 μM, Emax ≥150% and <300%) th at reduces cellular acetylation of Sirt1 substrates FoxO1 (induced by RANKL ) and histone 3 (1-10 μM; murine bone marrow macrophages) and exhibits in vivo efficacy in a murine atherosclerosis model (3.18 g/kg high-cholesterol diet; mice) and ovariectomy-induced bone loss in female mice (50 & 100 mg/kg via daily p.o.).

IC 50

SIRT1: 1 μM (EC1.5)

SRT3025 Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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SRT3025 Hydrochloride Suppliers

China 33 India 1 United States 8 USA 1 Global 43

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

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2070015-26-6, SRT3025 HydrochlorideRelated Search:

SRT3025 Hydrochloride

SIRTUIN MODULATOR 1;SRT3025 HCL

Inhibitor,Sirtuin,Sirtuin modulator1,inhibit,Sirtuin modulator-1,Sirtuin modulator 1

5-(3-Methoxypropyl)-2-phenyl-N-(2-(6-(pyrrolidin-1-ylmethyl)thiazolo[5,4-b]pyridin-2-yl)phenyl)thiazole-4-carboxamide hydrochloride

2070015-26-6