3-(BROMOMETHYL)-1,2-BENZISOXAZOLE
- Product Name
- 3-(BROMOMETHYL)-1,2-BENZISOXAZOLE
- CAS No.
- 37924-85-9
- Chemical Name
- 3-(BROMOMETHYL)-1,2-BENZISOXAZOLE
- Synonyms
- BMBI;3-Bromomethylbenzisoxazole;3-Bromoethylbenzo[o]isoxazole;3-(bromomethyl)-1,2-benzoxazole;3-(bromomethyl)benzo[d]isoxazole;3-(BROMOMETHYL)-1,2-BENZISOXAZOLE;3-BMBI 3-Bromomethyl Benzisoxazole;1,2-Benzisoxazole, 3-(bromomethyl)-;3-BROMOMETHYL-1,2-BENZISOXAZOLE(ZONISAMIDE INTERMEDIATE)
- CBNumber
- CB0468828
- Molecular Formula
- C8H6BrNO
- Formula Weight
- 212.04
- MOL File
- 37924-85-9.mol
3-(BROMOMETHYL)-1,2-BENZISOXAZOLE Property
- Melting point:
- 64-65°C
- Boiling point:
- 302.5±17.0 °C(Predicted)
- Density
- 1.642±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Acetone, Chloroform, Dichloromethane, Ethyl Acetate
- form
- Solid
- pka
- -3.26±0.30(Predicted)
- color
- Colourless Crystalline
- InChI
- InChI=1S/C8H6BrNO/c9-5-7-6-3-1-2-4-8(6)11-10-7/h1-4H,5H2
- InChIKey
- MAIKTETULSZRED-UHFFFAOYSA-N
- SMILES
- O1C2=C(C=CC=C2)C(CBr)=N1
- CAS DataBase Reference
- 37924-85-9(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B685250
- Product name
- 3-(Bromomethyl)-1,2-benzisoxazole
- Packaging
- 1g
- Price
- $705
- Updated
- 2021/12/16
- Product number
- HCH0027818
- Product name
- 3-BROMOMETHYL-BENZO[D]ISOXAZOLE
- Purity
- 95.00%
- Packaging
- 20MG
- Price
- $715
- Updated
- 2021/12/16
- Product number
- FB19248
- Product name
- 3-(Bromomethyl)-1,2-benzisoxazole
- Packaging
- 25mg
- Price
- $375
- Updated
- 2021/12/16
- Product number
- HCH0027818
- Product name
- 3-BROMOMETHYL-BENZO[D]ISOXAZOLE
- Purity
- 95.00%
- Packaging
- 200MG
- Price
- $1870
- Updated
- 2021/12/16
- Product number
- 7789
- Product name
- 3-(Bromomethyl)-1,2-benzisoxazole
- Packaging
- 100mg
- Price
- $1960
- Updated
- 2021/12/16
3-(BROMOMETHYL)-1,2-BENZISOXAZOLE Chemical Properties,Usage,Production
Chemical Properties
Colourless Crystalline Solid
Synthesis
37924-67-7
37924-85-9
General procedure for the synthesis of 3-(bromomethyl)benzo[d]isoxazole from 2-(benzo[d]isoxazol-3-yl)-2-bromoacetic acid: 2-(benzo[d]isoxazol-3-yl)-2-bromoacetic acid (Ref. J. Med. Chem. 2003, 46, 5428-5436; Chem. Pharm. Bull. 1978, 26, 3498-3503) was slowly heated to 130 °C and stirred at this temperature for 30 min. A large amount of gas was observed to escape during the reaction. After completion of the reaction, the mixture was cooled to room temperature and filtered to obtain a brown crystalline product. Finally, the product was purified by column chromatography (eluent: hexane) to afford 3-(bromomethyl)benzo[d]isoxazole (2.3 g, 70% yield).
References
[1] Patent: US2005/267074, 2005, A1. Location in patent: Page/Page column 26; 45
[2] Patent: US4859691, 1989, A
[3] Patent: CN105399697, 2016, A. Location in patent: Paragraph 0161; 0163
3-(BROMOMETHYL)-1,2-BENZISOXAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-(BROMOMETHYL)-1,2-BENZISOXAZOLE manufacturers
- Product
- 3-(BROMOMETHYL)-1,2-BENZISOXAZOLE 37924-85-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11