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PYROQUILON

Product Name
PYROQUILON
CAS No.
57369-32-1
Chemical Name
PYROQUILON
Synonyms
CG 114;CORATOP;fongoren;cga49104;fongorene;Fungorene;FONGARENE;PYROQUILON;lilolidone;pyroquilone
CBNumber
CB0470517
Molecular Formula
C11H11NO
Formula Weight
173.21
MOL File
57369-32-1.mol
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PYROQUILON Property

Melting point:
112℃
Boiling point:
355.2±42.0 °C(Predicted)
Density 
1.25±0.1 g/cm3(Predicted)
vapor pressure 
1.6 x 10-4 Pa (20 °C)
storage temp. 
0-6°C
Water Solubility 
4000 mg l-1 (20 °C)
pka
1.81±0.20(Predicted)
CAS DataBase Reference
57369-32-1
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Safety

Hazard Codes 
Xn
Risk Statements 
22-52/53
Safety Statements 
61
WGK Germany 
2
RTECS 
UY9480000
HS Code 
29334900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
45650
Product name
Pyroquilon
Purity
PESTANAL
Packaging
250mg
Price
$52.5
Updated
2024/03/01
Usbiological
Product number
463303
Product name
Pyroquilon
Packaging
250mg
Price
$305
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0311386
Product name
1,2,5,6-TETRAHYDRO-4H-PYRROLO[3,2,1-IJ]QUINOLIN-4-ONE
Purity
95.00%
Packaging
5MG
Price
$495.63
Updated
2021/12/16
Crysdot
Product number
CD11102015
Product name
5,6-Dihydro-1H-pyrrolo[3,2,1-ij]quinolin-4(2H)-one
Purity
97%
Packaging
1g
Price
$666
Updated
2021/12/16
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PYROQUILON Chemical Properties,Usage,Production

Uses

Pyroquilon is used for the control of blast (Pyricularia oryzae) in rice.

Definition

ChEBI: A pyrroloquinoline that is 1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinoline in which the hydrogens at position 4 are replaced by an oxo group. A fungicide used to control rice blast, it is not approved wof use within the Eur pean Union.

Metabolic pathway

The fate of pyroquilon in rice and rats has been reported. Given the metabolic stability of cyclic amides, there are few options, other than hydroxylation, open for the metabolism of the compound. Its biotransformation involves initial hydroxylation at three sites in the molecule, followed by ring-opening, dehydration and further oxidation affording a somewhat complex picture. A study in rats revealed most of these metabolites but with some further metabolic degradation. The usual differences in conjugation were seen with mainly glucoside formation in plants and glucuronide and sulfate formation in animals.

Metabolism

Animals: Rapidly metabolized and eliminated via urine and feces. Residues in tissues were generally low, and there was no evidence for accumulation or retention of pyroquilon or its metabolites. Plants: Major metabolites in rice grain were 3,4-dihydro-4-hydroxy-2- oxoquinoline-8-acetic acid and two other acetic acid derivatives. Soil/Environment: DT50 (silty soil) 2, (sandy loam) 18 w. Kd 1.3–42 μg/g soil, little to moderately mobile. Photolysis in water, DT50 10 d.

Toxicity evaluation

Mammalian toxicology. Oral: Acute oral LD50 for rats 321, mice 581 mg/kg. Skin and eye: Acute percutaneous LD50 for rats >3100 mg/kg. Not a skin irritant, minimal eye irritant (rabbits). Not a skin sensitiser (guinea pigs). Inhalation LC50 (4 h) for rats >5.1 mg/l air. NOEL: (2 yr) for rats 22.5, mice 1.5 mg/kg b.w. daily; (1 yr) for dogs 60.5 mg/kg b.w. daily. ADI: 0.015mg/kg b.w. Other: Not teratogenic, not mutagenic, not oncogenic. Toxicity class: WHO (a.i.) II; EPA (formulation) II RC risk R22. Ecotoxicology. Birds: LC50 (8 d) for Japanese quail 794, chickens 431 mg/kg. LC50 (8 d) for Japanese quail >10000 mg/kg. Fish LC50 (96 h) for catfish 21, rainbow trout 13, perch 20, guppy 30 mg/l. Bees: Practically nontoxic to honeybees; LD50 (oral) > 20, (contact) > 1000 mg/bee. Daphnia LC50 (48 h) > 60 mg/L. Algae: No effect on Scenedemus acutus.

Degradation

Pyroquilon is stable to hydrolysis over a very wide pH range. It is degraded under conditions of aqueous photolysis with a DT50 of 10 days (PM). Details are not available.

PYROQUILON Preparation Products And Raw materials

Raw materials

Preparation Products

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PYROQUILON Suppliers

Canada 1 China 67 Germany 1 India 2 Japan 2 South Korea 1 Switzerland 1 United Kingdom 1 United States 7 Global 83
Kanto Chemical Co., Inc.
Tel
--
Fax
--
Email
reag-info@gms.kanto.co.jp
Country
Japan
ProdList
6756
Advantage
74
Wako Pure Chemical Industries, Ltd.
Tel
--
Fax
--
Email
labchem-tec@wako-chem.co.jp
Country
Japan
ProdList
6819
Advantage
80
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View Lastest Price from PYROQUILON manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
PYROQUILON 57369-32-1
Price
US $9.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2024-12-04
Hebei Mojin Biotechnology Co., Ltd
Product
PYROQUILON 57369-32-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-17

57369-32-1, PYROQUILONRelated Search:

Albendazole Praziquantel Boscalid FLUSULFAMIDE IMINOCTADINE TRIS(ALBESILATE) PYROQUILON

  • PYROQUILON
  • 2,1-ij)quinolin-4-one,1,2,5,6-tetrahydro-4h-pyrrolo(
  • cga49104
  • fongoren
  • fongorene
  • lilolidone
  • pyroquilone
  • 1,2,5,6-TETRAHYDROPYRROL[3,2,1-IJ]QUINOLINE-4-ON
  • PYROQUILON PESTANAL (1,2,5,6-TETRA- HYDR
  • pyroquilon (bsi,draft-iso)
  • pyroquilon (ISO) 1,2,5,6-tetrahydropyrrolo[3,2,1-ij]quinolin-4-one
  • 1,2,5,6-Tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
  • 4-Lilolidine
  • Fungorene
  • 1,2,5,6-TETRAHYDROPYRROLO(3,2,1-IJ)QUINOLIN-4-ONE
  • Pyroquilon Standard
  • 4,5-dihydro-1H-pyrrolo[3,2,1-ij]quinolin-6(2H)-one
  • CG 114
  • 4-Oxo-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinoline
  • Pyroquilon 0.2
  • CORATOP
  • FONGARENE
  • 5,6-dihydro-1H-pyrrolo[3,2,1-ij]quinolin-4(2H)-one
  • Pyroquilon @100 μg/mL in Methanol
  • Pyroquilon@1000 μg/mL in Acetonitrile
  • 4H-Pyrrolo[3,2,1-ij]quinolin-4-one, 1,2,5,6-tetrahydro-
  • 1-azatricyclo[6.3.1.0?12]dodeca-4(12),5,7-trien-11-one
  • L16665000CY Pyroquilon 10μg/mLin Cyclohexane
  • 57369-32-1
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