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MTS Reagent

Product Name
MTS Reagent
CAS No.
138169-43-4
Chemical Name
MTS Reagent
Synonyms
3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium;MTS(dye);FEMA 2696;METOLOSE(R);MTS Reagent;'TYLOSE'(R) MH 300;'TYLOSE'(R) MH 1000;TIANFU-CHEM METHYL CELLULOSE;MTS Reagent, cell proliferation assay reagent;5-[3-(Carboxymethoxy)phenyl]-3-(4,5-dimethyl-2-thiazolyl)-2-(4-sulfophenyl)-2H-tetrazoliuminnersal
CBNumber
CB0474717
Molecular Formula
C20H17N5O6S2
Formula Weight
487.515
MOL File
138169-43-4.mol
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MTS Reagent Property

form 
powder
InChIKey
APRZHQXAAWPYHS-UHFFFAOYSA-N
SMILES
[N+]1(=NC(C2=CC=CC(OCC(=O)O)=C2)=NN1C1=CC=C(S([O-])(=O)=O)C=C1)C1SC(C)=C(C)N=1
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Safety

Safety Statements 
24/25
WGK Germany 
3
RTECS 
FJ5959000
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Chemenu
Product number
CM327729
Product name
4-[5-[3-(carboxymethoxy)phenyl]-3-(4,5-dimethyl-1,3-thiazol-2-yl)tetrazol-3-ium-2-yl]benzenesulfonate
Purity
95%+
Packaging
1g
Price
$234
Updated
2021/12/16
DC Chemicals
Product number
DC8240
Product name
MTS
Purity
>97%
Packaging
100mg
Price
$300
Updated
2021/12/16
DC Chemicals
Product number
DC8240
Product name
MTS
Purity
>97%
Packaging
250mg
Price
$600
Updated
2021/12/16
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MTS Reagent Chemical Properties,Usage,Production

Description

MTS reagent is one of the most common water-soluble tetrazolium reagents that are widely used to quantify cell viability by absorption spectrophotometry. A variety of tetrazolium inner salts are used for determining cell viability in proliferation assays by monitoring their color changes. Metabolically active cells reduce colorless tetrazolium inner salts into the colored formazan products that might be either soluble or insoluble in cell culture media depending on the structures of tetrazolium reagents. The conversion of tetrazolium inner salts to formazans is thought to be carried out by NAD(P)H-dependent dehydrogenase enzymes.

Biological Activity

Tetrazolium inner salt used for determining cell viability in proliferation assays. Reduced in metabolically active cells to a colored formazan product that is soluble in cell culture media. This conversion is thought to be carried out by NAD(P)H-dependent dehydrogenase enzymes.

References

[1] MORVA MANSOURY. The edge effect: A global problem. The trouble with culturing cells in 96-well plates[J]. Biochemistry and Biophysics Reports, 2021, 26: Article 100987. DOI:10.1016/j.bbrep.2021.100987.
[2] VICTOR AKPE. Profiling the Neoplasm Microenvironment of Silica Nanomaterial-Derived Scaffolds of Single, 2-, and 3-Composite Systems.[J]. Assay and drug development technologies, 2021, 19 3: 191-203. DOI:10.1089/adt.2020.1020.
[3] YUTANG WANG. A Modified MTS Proliferation Assay for Suspended Cells to Avoid the Interference by Hydralazine and β-Mercaptoethanol.[J]. Assay and drug development technologies, 2021, 19 3: 184-190. DOI:10.1089/adt.2020.1027.

MTS Reagent Preparation Products And Raw materials

Raw materials

Preparation Products

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MTS Reagent Suppliers

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View Lastest Price from MTS Reagent manufacturers

Dideu Industries Group Limited
Product
Methyl cellulose 138169-43-4
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-08-16

138169-43-4, MTS ReagentRelated Search:


  • 5-[3-(Aarboxymethoxy)phenyl]-3-(4,5-dimethyl-2-thiazolyl)-2-(4-sulfophenyl)-2H-tetrazolium inner salt
  • 2H-TetrazoliuM,5-[3-(carboxyMethoxy)phenyl]-3-(4,5-diMethyl-2-thiazolyl)-2-(4-sulfophenyl)-,inner salt
  • 5-[3-(Carboxymethoxy)phenyl]-3-(4,5-dimethyl-2-thiazolyl)-2-(4-sulfophenyl)-2H-tetrazolium inner salt
  • 4-{5-[3-(Carboxymethoxy)phenyl]-3-(4,5-dimethyl-1,3-thiazol-2-yl)-2H-tetrazol-3-ium-2-yl}benzenesulfonate
  • METOLOSE(R)
  • 'TYLOSE'(R) MH 1000
  • 'TYLOSE'(R) MH 300
  • MTS(dye)
  • 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium
  • FEMA 2696
  • MTS Reagent, cell proliferation assay reagent
  • 4-(5-(3-(carboxymethoxy)phenyl)-3-(4,5-dimethylthiazol-2-yl)-2H-tetrazol-3-ium-2-yl)benzenesulfonate
  • TIANFU-CHEM METHYL CELLULOSE
  • 5-[3-(Carboxymethoxy)phenyl]-3-(4,5-dimethyl-2-thiazolyl)-2-(4-sulfophenyl)-2H-tetrazoliuminnersal
  • 4-[5-[3-(carboxymethoxy)phenyl]-3-(4,5-dimethyl-1,3-thiazol-2-yl)tetrazol-3-ium-2-yl]benzenesulfonate
  • MTS Reagent
  • 138169-43-4
  • C20H17N5O6S2