UPGL00004

ChemicalBook > CAS DataBase List > UPGL00004

Product Name: UPGL00004
CAS No.: 1890169-95-5
Chemical Name: UPGL00004
Synonyms: UPGL00004;UPGL00004,UPGL-00004;2-Phenyl-N-(5-(4-((5-(2-phenylacetamido)-1,3,4-thiadiazol-2-yl)amino)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)acetamide;Benzeneacetamide, N-[5-[4-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]amino]-1-piperidinyl]-1,3,4-thiadiazol-2-yl]-;2-Phenyl-N-(5-(4-((5-(2-phenylacetamido)-1,3,4-thiadiazol-2-yl)amino)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)acetamide , UPGL00004
CBNumber: CB04800860
Molecular Formula: C25H26N8O2S2
Formula Weight: 534.66
MOL File: 1890169-95-5.mol

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UPGL00004 Property

Density: 1.460±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: 2mg/mL, clear
form: Solid
pka: 9.23±0.50(Predicted)
color: Off-white to gray

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0068007
Product name: UPGL00004
Purity: ≥98.0%
Packaging: 5mg
Price: $250
Updated: 2021/12/16

ChemScene

Product number: CS-0068007
Product name: UPGL00004
Purity: ≥98.0%
Packaging: 50mg
Price: $1200
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573368
Product name: UPGL00004
Purity: >98%
Packaging: 100mg
Price: $1208.7
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573368
Product name: UPGL00004
Purity: >98%
Packaging: 250mg
Price: $2395.3
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573368
Product name: UPGL00004
Purity: >98%
Packaging: 1g
Price: $4766.8
Updated: 2021/12/16

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UPGL00004 Chemical Properties,Usage,Production

Biological Activity

UPGL00004 is a potent glutaminase C (GAC) inhibitor with IC50 of 29 nM, more selective for GAC than GLS2.

in vitro

Administration of UPGL00004 in combination with the anti-VEGF antibody bevacizumab effectively inhibited triple-negative breast cancer cell growth and tumor growth.

in vivo

Administration of UPGL00004 in combination with the anti-VEGF antibody bevacizumab inhibited tumor growth in a human xenograft model of breast cancer.

target

< td style="border-bottom: 1px dotted #ccc;padding: 5px;"> 29 nM

Target	Value
glutaminase C (Cell-free assay)

UPGL00004 Preparation Products And Raw materials

Raw materials

Preparation Products

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UPGL00004 Suppliers

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1890169-95-5, UPGL00004Related Search:

UPGL00004

UPGL00004,UPGL-00004

Benzeneacetamide, N-[5-[4-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]amino]-1-piperidinyl]-1,3,4-thiadiazol-2-yl]-

2-Phenyl-N-(5-(4-((5-(2-phenylacetamido)-1,3,4-thiadiazol-2-yl)amino)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)acetamide

2-Phenyl-N-(5-(4-((5-(2-phenylacetamido)-1,3,4-thiadiazol-2-yl)amino)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)acetamide , UPGL00004

1890169-95-5