ChemicalBook > CAS DataBase List > DJ-V159

DJ-V159

Product Name
DJ-V159
CAS No.
2253744-53-3
Chemical Name
DJ-V159
Synonyms
DJ-V159;DJ-V159;DJ-V 159;DJV159,Inhibitor,Androgen Receptor,inhibit,DJ V 159;1,3-Benzenedicarboxamide, N1,N3-bis[4-cyano-3-(trifluoromethyl)phenyl]-
CBNumber
CB04804691
Molecular Formula
C24H12F6N4O2
Formula Weight
502.37
MOL File
2253744-53-3.mol
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DJ-V159 Property

storage temp. 
RT
solubility 
Soluble in DMSO (up to 60 mg/ml).
form 
solid
color 
Off-white
Stability:
Stable for 2 years from date of purchase? as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
6645
Product name
DJ-V159
Purity
≥98%(HPLC)
Packaging
10
Price
$109
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573178
Product name
DJ-V-159
Purity
>98%
Packaging
100mg
Price
$838.1
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573178
Product name
DJ-V-159
Purity
>98%
Packaging
250mg
Price
$1431.4
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573178
Product name
DJ-V-159
Purity
>98%
Packaging
1g
Price
$2691.1
Updated
2021/12/16
DC Chemicals
Product number
DC12040
Product name
DJ-V-159
Purity
>98%
Packaging
1g
Price
$1800
Updated
2021/12/16
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DJ-V159 Chemical Properties,Usage,Production

Description

GPRC6A? is the receptor for osteocalcin as well as structurally unrelated ligands including L-amino acids, cations and anabolic steroids.1?GPRC6A is a potential therapeutic target for treating type 2 diabetes.2 DJ-V 159 (2253744-53-3) is an agonist at GPRC6A which activates ERK and upregulates cAMP levels in HEK-193 cells expressing GPRC6A. It stimulates insulin secretion in mouse β-cells and lowers blood glucose in mouse models.3

storage

Store at RT

References

1) Pi and Quarles (2012),?Multiligand specificity and wide tissue expression of GPRC6A reveals new endocrine networks; Endocrinology,?153?2062 2) Pi?et al.?(2016),?GPRC6A: Jack of all metabolism (or master of none); Mol. Metab.,?6?185 3) Pi?et al.?(2018),?Computationally identified novel agonists for GPRC6A; PLoS One,?13?e0195980

DJ-V159 Preparation Products And Raw materials

Raw materials

Preparation Products

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DJ-V159 Suppliers

Shanghai Lollane Biological Technology Co.,Ltd.
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InvivoChem
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2253744-53-3, DJ-V159Related Search:


  • DJ-V159
  • DJ-V159;DJ-V 159
  • 1,3-Benzenedicarboxamide, N1,N3-bis[4-cyano-3-(trifluoromethyl)phenyl]-
  • DJV159,Inhibitor,Androgen Receptor,inhibit,DJ V 159
  • 2253744-53-3